The International Organization for the Study of Inflammatory Bowel Disease (IOIBD) aimed to identify a set of endpoints that can be used to determine the efficacy of anti-fibrosis drugs.
Source: National Library Of Medicine
Transgender, nonbinary, and gender-expansive people who were assigned female or intersex at birth have abortions. This study aimed to fill existing evidence gaps on abortion experiences and preferences. If they were to need an abortion today, respondents preferred medication abortion over surgical abortion in a 3:1 ratio. These data contribute substantially to the evidence base on individual experiences of and preferences for abortion care for transgender, nonbinary, and gender-expansive people.
Source: The American Journal of Obstetrics and Gynecology (AJOG)
Of the 118 residents tested among approximately 130 residents from Facility A during February 28-March 16, 2020, 101 (86%) were found to test positive for SARS-CoV-2. Most (90.2%) symptomatic residents had elevated temperature, change
Source: National Library Of Medicine
Chemotherapy-induced peripheral neuropathy (CIPN) is commonly experienced in children. P-CIN is an electronic measure for assessing CIPN in children who received neurotoxic chemotherapy. For 9 of 14 items, responses ranged from 0 to 4 or 5 for toe numbness and pick up a coin and three of four pain items were 0 to 3.
The SMART protocol consists of a short accelerated course of radiotherapy followed by extrapleural pneumonectomy. Patients received 25 Gy in five daily fractions over 1 week to the entire ipsilateral hemithorax. 47% of patients had 30-day perioperative grade 3–4 events
Source: The Lancet
Inclusion body myositis is most frequent in patients older than 50 years. In this pilot study, we aimed to test the efficacy of sirolimus in patients with the disease. The study was a randomized, double-blind, placebo-controlled, proof-of-concept, phase 2b trial. Canker sores were the most frequent side-effect and were mainly mild or moderate in ten patients.
Source: The Lancet
RVH is defined as elevated blood pressure caused by kidney hypoperfusion. Digital subtraction angiography is the gold standard method for the diagnosis of RVH
Source: Springer Link
Anthracycline-induced cardiotoxicity (AIC) is a serious adverse effect among cancer patients. The central mechanism of AIC is irreversible mitochondrial damage. Animals receiving RIPC before doxorubicin (RIPC-Doxo) had a significantly higher LVEF at Week 16 than those treated with no pretreatment (Untreated-Dxo) This was mainly due to conserved regional contractile function.
Source: Oxford Academic
Tranexamic acid reduces bleeding during soft tissue surgeries and reduces postoperative ecchymosis and edema experienced by surgical patients.No statistical difference was seen in mean edema scores between groups.
Source: Dermatologic Surgery
Research results show that experiences with pay-for-performance approaches in ophthalmology are limited. Identified approaches differ with regard to quality and incentive elements restricting comparability
Source: National Library Of Medicine