Colorectal cancer in 18- to 49-year-olds: rising rates, presentation, and outcome in a large integrated health system
New guidelines recommend screening should begin at age 45. Younger patients are more likely to have metastases and to need multimodality treatment.
Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial
RAPIDO trial aimed to reduce distant metastases without compromising locoregional control. Participants were recruited from 54 centers in the Netherla...
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