Insomnia is a common sleep disorder that can make it hard to fall asleep and stay asleep. Most adults need seven to eight hours of sleep a night, but some people have long-term insomnia lasting for a month or more. Simple changes in your daily habits can often help you sleep through the night.
Source: Mayo Clinic
Glucagon inhibits digestive motility and is used for endoscopic premedication. Its effect on cardiopulmonary function during endoscopy has not yet been fully investigated. Blood pressure, arterial oxygen saturation, and a number of retching episodes were not different between the groups.
The study looked at the literature on methods of assessing patient experience in GI endoscopy. Most measures focused on pain, discomfort, anxiety, and embarrassment. Three studies explored wider aspects of experience, including preparation, unit organization, and endoscopist preference
Source: National Library Of Medicine
Unsedated transnasal endoscopy (TNE) has been suggested as an alternative to conventional TOE. This study aimed to determine the advantages of TNE in patients who have previously undergone unsedated conventional toE.
Source: National Library Of Medicine
The study aims to identify the clinical and demographic factors influencing the time taken for viral clearance in patients with COVID-19 to determine the optimal isolation period. Younger patients who recovered from SARS-CoV-2 took less time to clear the virus than older patients.
Source: National Library Of Medicine
In total, 35/124 (26.6%) samples were RT-PCR positive, with 33/35 positive by NPS. A third or more of pure saliva samples from symptomatic patients were thick, stringy, and difficult to pipet. Our study highlighted the need to optimize collection and processing before saliva can be used for high-volume testing.
Source: National Library Of Medicine
Quantitative reverse transcription-PCR (RT-qPCR) is the preferred methodology for viral RNA detection. This study shows that RT-ddPCR allows the detection of as low as 10.3 copies of a SARS-COV-2 E-gene per sample with a higher level of accuracy and precision, especially at low concentration.
Source: National Library Of Medicine
IgG response was studied in relation to duration and severity of illness. The igG detection rate was higher in patients with severe disease. The BPL inactivated virus-based ELISA could detect IgG antibodies early and in a significant proportion of patients suggesting its potential utility as a supplement to the currently used viral RNA detection tests.
Source: National Library Of Medicine
SARS-CoV-2 has been arguably the most important public health concern worldwide in 2020. We used a random-effects model to estimate pooled seroprevalence and then extrapolated the findings to the global population (for 2020) This study showed that SARS- virus-2 seroprevalence varied markedly among geographic regions, as might be expected early in a pandemic.
Source: National Library Of Medicine
Assessment of the RealStar® SARS-CoV-2 RT-PCR Kit Research Use Only (Altona) compared with the WHO-PCr. Assay showed a slightly higher sensitivity with a limit of detection at 625 copies/mL instead of 1250 copies/L for the WHO. The overall percent agreement between RealStar and WHO- PCR on 83 clinical samples was 97.6% (81/83) with sensitivity at 97.8%.
Source: National Library Of Medicine
In total, 625 patients were screened for SARS-CoV-2 using a combination of phone questionnaires, RT-PCR and chest computed tomography. Of the 625 patients, 520 scans (83.2%) were interpreted as normal. 18 scans (2.88%) had indeterminate features of COVID-19; and 86 (13.76%) had atypical features of the SARS virus. After surgery, none of the patients developed signs or symptoms suspicious of SARS that would indicate the need for surgery.
Source: National Library Of Medicine
Plasma SARS-CoV-2 RNA seems to be associated with a worse COVID-19 outcome. Viremic patients were more frequently affected by hematological malignancies and had a higher viral load in respiratory samples
Source: National Library Of Medicine
Methods: We designed primers specific to the orf1ab and S genes of SARS-CoV-2. Total viral RNA was extracted using the QIAamp Viral RNA Mini Kit. Assay: 58 specimens were confirmed to be positive and 72 were negative by RT-LAMP. sensitivity was 100% (95% CI 92.3%-100%), specificity 100% and sensitivity (95%)
Source: National Library Of Medicine
Millions of people have been affected globally by SARS-CoV-2. The percentage of patients who delivered vaginally was higher than those who experienced a cesarean section. Maternal and neonatal death rates were found to be 5% and 6%, respectively.
Source: National Library Of Medicine
Cancer control plans in Africa were investigated. Ten plans discussed cancer control in the context of non-communicable diseases. Pediatric cancer was mentioned in 7 national plans, representing 5127 children, or 13% of the estimated continental burden for children aged 0-14 years. Palliative care was itemized in four budgets.
Source: National Library of Medicine
This study assesses national trends in fourth-year medical student radiation oncology clerkships over the past 6 academic years. Over half of clerkship experiences continue to lack a structured didactic curriculum.
Source: National Library Of Medicine
Rheumatology in Korea has rapidly advanced in the 24 years since the subspecialty board certification program was established. In 2015, there were 311 practicing rheumatologists on the list of KCR members.
Source: National Library of Medicine
Renal artery fibromuscular dysplasia (FMD) can cause arterial stenosis, dissection, and aneurysm of renal arteries. The incidence of branch FMD was higher in children than in adults. Endovascular treatment with balloon angioplasty can be used to treat FMD.
Source: Springer Link
Severe acute respiratory syndrome coronavirus 2 causes cardiac injury in nonpregnant women. The study retrospectively reviewed the paper records of 15 pregnant women with coronavirus disease in 2019, who developed a myocardial injury in a single tertiary care hospital in the Dominican Republic. The study showed coronavirus disease 2019 induced myocardial injury and left ventricular dysfunction in pregnant women.
Source: The American Journal of Obstetrics and Gynecology (AJOG)
It is unclear whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) gains access to the CNS. We investigated the brain tissue of patients who died from COVID-19 for glial responses, inflammatory changes, and the presence of SARS- CoV- 2 in the brain. There was no evidence of CNS damage directly caused by the virus. The generalisability of these findings needs to be validated in future studies.
Source: The Lancet
The study looked at 108 mother-child dyads from three to four years old. Higher levels of maternal depressive symptoms predicted faster transitions into sadness only for girls but not for boys. Girls of mothers with elevated depressive symptoms showed impairment in antecedent-focused emotion regulation of sadness.
Source: Springer Link
0.5-mg intravitreous ranibizumab vs pan-retinal photocoagulation (PRP) over 5 years for PDR. Secondary outcomes included peripheral visual field loss, development of vision-impairing diabetic macular edema, and ocular and systemic safety.
Source: National Library Of Medicine
The safety of a new botulinum toxin (HU-014) was confirmed through animal experiments. HU-014 was non-inferior to existing on botulinum toxin A in the treatment of glabellar lines at a 1:1 dose ratio.
Source: Dermatologic Surgery
The median weaning time from the procedure, to discontinuation of mechanical circulatory or respiratory support, was 2 days. Device success was achieved in 238 (93.7%) patients with a significant reduction in MR.
Source: National Library Of Medicine
The prevalence of reporting complications in spinal surgeries is highly heterogeneous. Almost one-third of spine surgical studies did not report complications in their results in spite of reporting clinical outcomes
Source: National Library Of Medicine
An estimated 27738 emergency department visits with an average annual incidence of 3.8 per 100,000 US population in 17 years were reported. Over half of genital injuries (55.2%) were associated with climbing apparatus.
Source: Urology
Sedation with propofol is associated with a high acceptance rate in upper gastrointestinal endoscopy. So far, however, there is no valid data on whether the use of Propofol can increase the general quality of the endoscopic examination.
Source: National Library Of Medicine
Examining the available evidence on safety, competency and cost-effectiveness of nursing staff providing gastrointestinal (GI) endoscopy services. The number of publications in the field of non-specialist gastrointestinal endoscopies reached a peak between 1999 and 2001.
Source: National Library Of Medicine
The majority of gastrointestinal endoscopists in the UK routinely use intravenous sedation prior to the diagnostic upper gastrointestinal endoscopes. 100 patients were randomized to receive sedation or no sedation.
Source: National Library Of Medicine
Music has little influence on patients' experience of gastrointestinal endoscopy. The majority of patients felt music to be helpful and expressed a preference for music during any future examination.
Source: National Library Of Medicine
Capsule endoscopy is considered the diagnostic procedure of choice in patients with obscure gastrointestinal bleeding. Blood in the lumen was the only positive finding at capsule endoscopies in 34 cases.
Source: National Library Of Medicine
The pooled sensitivity and specificity of magnifying endoscopy to predict Helicobacter pylori infection were 0.89 [95% confidence interval (CI) 0.87-0.91] and 0.82 (95%CI 0.79- 0.85), respectively, with an AUC of 0.9461.
Source: National Library Of Medicine
The study compared cytological samples from endoscopic biopsies using "imprint" and "squash" techniques. The same diagnosis was obtained with the squash technique in 65% of the cases. Cytology was considered complementary to histology for gastric spiral organisms and mast cells.
Source: National Library Of Medicine
Rising demand for. general diagnostic upper gastrointestinal endoscopy in the UK is outgrowing the capacity of doctors. provide this service within a reasonable time.
Source: National Library Of Medicine
The cecal intubation rate (CIR) is a widely accepted key performance indicator (KPI) in colonoscopy but lacks a universal calculation method. We assessed whether differences in CIR calculation methods could have an impact on perceived trainee outcomes.
Source: National Library Of Medicine
Traditional white-light endoscopy cannot reliably distinguish between small adenomatous and hyperplastic colon polyps. HDWL endoscope and i-Scan may improve in vitro characterization of small colon polyps.
Source: National Library Of Medicine
The study looked at attitudes and behavior before and after negative serological test results for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies. Participants perceived the disease as a severe health threat and acknowledged that the protective measures were appropriate.
Source: National Library Of Medicine
In hospitals, these delays lead to poor patient flow and nosocomial transmission. Rapid, accurate tests are urgently needed in preparation for the next wave of the pandemic. We did a prospective, interventional, non-randomized, controlled study of molecular point-of-care testing in patients with suspected COVID-19 at Southampton General Hospital.
Source: National Library Of Medicine
Most patients, especially critically ill patients, had significant changes in nutrition-related parameters and inflammatory markers. Critically ill patients and those with higher nutrition risk had a higher risk of mortality and longer stay in hospital. Only 84 of 342 patients with high nutrition risk received nutrition support.
Source: National Library Of Medicine
duration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the upper respiratory tract is extremely variable. We investigated this relation in the northeastern Italian province of Udine. 39 483 RT-PCR tests were conducted on 23 778 individuals, and 974 individuals had a positive test result.
Source: National Library Of Medicine
To address this pandemic broad testing with an easy, comfortable and reliable testing method is of utmost concern. Nasopharyngeal (NP) swab sampling is the reference method though hampered by international supply shortages. A strong correlation was found between the viral RNA loads of the paired swabs.
Source: National Library Of Medicine
In this cross-section study, we evaluated COVID-19 seroprevalence in military police forces of 10 major cities in the Rio Grande does Sul, South of Brazil. The sample size consisted of 1,592 military workers (33.6% of the study population) They were mostly men (81.2%) and young (median 34 years old) Most had been asymptomatic (75.3%) during a pandemic.
Source: National Library Of Medicine
The study involved 1355 participants from 11 governorates and 1136 individuals visiting Palestinian medical laboratories between 1st May 2020 and 9th July 2020 for a routine check-up. The random sample of Palestinians living in the West Bank yielded 0% seroprevalence with 95% and an adjusted CI (0.001325% to 0.011566%) The study suggests that as of mid-June 2020, the outbreak in Palestine persists low and is inadequate to provide herd immunity.
Source: National Library Of Medicine
COVID-19 has put the in-vitro-diagnostic community under an unprecedented spotlight, with a global requirement for accurate SARS-CoV-2 tests. This review outlines technological responses to this need and the analytical considerations required for their translation to routine use
Source: National Library Of Medicine
The study examined seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the industry workers population sample. Serological testing for antibodies (Immunoglobulin G (IgG) and Immunoglobulins M (IGM) was conducted on 1494 factory employees living in Croatia.
Source: National Library Of Medicine
There is an urgent need to develop a vaccine for prophylaxis of COVID-19 and for other future epidemics. This review describes patented vaccines for SARS and MERS-CoV and vaccines developed and approved for emergency use against the new coronavirus
Source: National Library Of Medicine
The Ambulatory Pediatric Association sponsored a meeting for academic pediatric hospitalists in November 2003. The purpose of the meeting was to discuss and to define roles. Pediatric hospital medicine is a rapidly growing field, with an estimated 800 to 1000 pediatric hospitalists currently practicing.
Source: National Library of Medicine
This is the first review of the literature pertaining to teaching radiation oncology to medical undergraduates. Teachers should begin early in the undergraduate process, should be mandatory for all students, and should impart knowledge relevant to future general practitioners.
Source: National Library Of Medicine
The ACR pediatric rheumatology Top 5 is one of the first pediatric subspecialty-specific Choosing Wisely Top 5 lists. Items focused on testing for antinuclear antibodies, autoantibody panels, Lyme disease, methotrexate toxicity monitoring, and the use of routine radiographs.
Source: National Library of Medicine
First-trimester ultrasound scans were introduced to China for nearly 20 years. We aimed to determine the performance of routine first- Trimester scans using a standardized Anatomic protocol. Scans at 11 to 13+6 weeks were performed in a single center during a 7-year span. During the first trimester, 37.7% of cardiac defects were identified. This included 57.9% of major cardiac defects and 2.6% of mild cardiac defects.
Source: The American Journal of Obstetrics and Gynecology (AJOG)
We aimed to assess the safety and efficacy of galcanezumab, an antibody to calcitonin gene-related peptide. The primary endpoint was the overall mean change from baseline in a number of monthly migraine headache days during the 3-month treatment period.
Source: The Lancet
Models of transdiagnostic family emotion processes recognize parents' emotion-related characteristics and behaviors as key contributors to child emotional development and psychological functioning. We examined how mothers' emotion dysregulation predicted their emotion socialization practices and children's emotion regulation over time, in relation to later child anxiety.
Source: Springer Link
The case involves a community looking for a way to get back on its feet after years of declining health. The police department is focusing on helping those who come in contact with police in need.
Source: National Library Of Medicine
Many patients complain of prominent vertical veins in the center of their forehead. Previous attempts to treat these with external laser, sclerotherapy, and phlebectomy have not been successful.
Source: Dermatologic Surgery
Study looked at 14 studies with a total of 999,179 participants. Low serum 25,OHD was associated with higher rate of COvid-19 infection compared to the control group
Source: National Library Of Medicine
Gene therapy has been proposed as a possible approach to improve or augment bone healing. Small animal models that support the use of gene therapy do not recapitulate key features of a critical or complex fracture environment. Larger animal models are therefore a key step on the path to clinical translation of the technology
Robotic-assisted transvaginal surgery is a feasible and alternative to laparoscopic surgery. We report on two patients with stage II apical pelvic organ prolapse who underwent the new technique.
Source: Urology
Nurses were more thorough than doctors in examining the stomach and oesophagus. Patients were more satisfied with nurses after one day of endoscopy than after one month
Source: National Library Of Medicine
The position of capsule endoscopy (CE) in the diagnostic algorithm of obscure gastrointestinal bleeding is unclear. We conducted a trial in which patients were randomized to undergo one or other exploration
Source: National Library Of Medicine
Drinking water up to 90 minutes prior to endoscopy is safe, but milk should be discouraged because of suboptimal mucosal views, authors say. The study found no difference between water and milk in residual gastric volume or pH
Source: National Library Of Medicine
Unsedated transnasal upper endoscopy (TNE) has been suggested as a more comfortable and safer method than unsedated transoral endoscopes (TOE) The current study aimed to assess the tolerability, safety, and efficacy of TNE in endoscopy naive patients.
Source: National Library Of Medicine
Propofol sedation bears the risk of complications such as respiratory as well as cardiopulmonary insufficiency including sedation-induced death. Conclusion: This large prospective survey shows that propofol. sedation in gastrointestinal endoscopy is a safe procedure with a low. the potential of risk in daily routine.
Source: National Library Of Medicine
The study was designed to see the effect of sedation on endoscopy-induced arterial oxygen desaturation. 90 consecutive patients scheduled for diagnostic upper gastrointestinal endoscopes were divided into two groups. Patients in the first group were sedated with midazolam 0.1 mg/kg, propofol 1mg/kg and fentanyl 1 microg/kg intravenously, while the second group received saline as a placebo.
Source: National Library Of Medicine
The over-the-scope clip (OTSC) has been increasingly utilized for the management of gastrointestinal (GI) bleeding. This systematic review showed high rates of definitive hemostasis, technical success, and clinical success, along with low rebleeding rates when OTSCs were used for the treatment of GI bleeding.
Source: National Library Of Medicine
Premedication with pronase, dimethylpolysiloxane, and sodium bicarbonate improves visibility during upper gastrointestinal (UGI) endoscopy. The optimal time for this combination to take effect is unknown. We investigated the optimal time of pre-UGI premedication.
Source: National Library Of Medicine
Premedication with pronase, dimethylpolysiloxane, and sodium bicarbonate improves visibility during upper gastrointestinal (UGI) endoscopy. The optimal time for this combination to take effect is unknown. We investigated the optimal time of pre-UGI premedication.
Source: National Library Of Medicine
Diagnostic esophagogastroduodenoscopy (EGD) is uncomfortable for most patients. We determined the efficacy of alprazolam, administered orally or sublingually, as premedication for sedation during EGD.
Source: National Library Of Medicine
The study objective was to characterize the non-physician performance of lower and upper endoscopic procedures. Bibliographical searches were conducted in Medline, EMBASE, and Cochrane Library databases. outcomes and rate ratios were determined.
Source: National Library Of Medicine
The Optima SARS-CoV-2 Assay has only recently received Emergency Use Authorization (EUA) by the Food and Drug Administration (FDA) TMA provides an effective, highly sensitive means of detection of SARS in nasopharyngeal specimens
Source: National Library Of Medicine
Conjunctivitis is presented as the sole symptom of a new coronavirus disease 2019 (COVID-19) in an emergency health care worker. The patient's first application was to the ophthalmology clinic due to redness, stinging, tearing, and photophobia for one day in the right eye
Source: National Library Of Medicine
The assay may be useful for rapid diagnosis of the severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) because of the easy performance and the option to bypass RNA extraction. Using isolated RNA variplex™ RT-LAMP showed a sensitivity of 75% compared to LightMix E gene RT-PCR but contrary to the latter it produced no false-positive results.
Source: National Library Of Medicine
Nursing homes and other long-term care facilities have been disproportionately impacted by the COVID-19 pandemic. Strategies are urgently needed to reduce transmission in these high-risk populations. This decision analytical modeling study developed an agent-based susceptible-exposed-infectious (asymptomatic/symptomatic)-recovered model.
Source: National Library Of Medicine
There is no specific treatment or approved vaccine for the coronavirus disease 2019 (COVID-19) There is a global pandemic with substantial morbidity and mortality. Older age, obesity, hypertension, cardiovascular disease, and diabetes mellitus increase the risk of hospitalization and death.
Source: National Library Of Medicine
The novel coronavirus disease 2019 (COVID-19) pandemic has been at its peak for the past 8 months and has affected more than 215 countries. India is now the second most affected nation with more than 48,000,000 cases and 79,000 deaths. Despite this, and the fact that it is a lower-middle-income nation, the number of deaths is almost one-third that of the United States and one-half that of Brazil.
Source: National Library Of Medicine
This case highlights the importance of clinical suspicion of SARS-CoV-2 infection in diagnosis and infectivity assessment. We suggest a collection of BAL fluid when consecutive nasopharyngeal swabs are negative.
Source: National Library Of Medicine
A combined swab may be recommended as a more appropriate specimen for both diagnosis and monitoring of COVID-19 treatment by rRT-PCR for assessing virus clearance. Implementing combined swabs globally will definitely help in the management and control of the pandemic, as it is the need of the hour.
Source: National Library Of Medicine
During the COVID-19 pandemic, the health care workers at the frontline have been largely exposed to infected patients. The cumulative incidence of SARS-CoV-2 infection among the screened HCWs was 11.33% (9.72-13.21) Being a former smoker and having a BMI was positively associated with infection.
Source: National Library Of Medicine
Lebanese paediatricians diagnosed and managed gastro-oesophageal reflux disease (GERD) in infants and children. Only 2.1% followed the guidelines on the evidence-based management of GERD
Source: National Library of Medicine
US radiation oncology residents in the Association of Residents in Radiation Oncology database were sent an online questionnaire regarding brachytherapy training. Of PGY4/5 respondents, 96% (86 of 90) believed learning brachyTherapy during residency was important.
Source: National Library Of Medicine
IRT applications have markedly increased within rheumatology over the past decades. To date, IRT has primarily been applied to patient-reported outcomes
Source: National Library of Medicine
The disease caused by the severe acute respiratory syndrome coronavirus 2 was named coronavirus disease 2019 and classified as a global public health emergency. The study evaluated severe acute respiratory syndrome coronavirus 2 infections as a risk factor for early pregnancy loss. Coronavirus disease 2019 was compared between women with spontaneous abortion and those with ongoing pregnancy. No difference in the incidence of symptoms was noted between the 2 groups.
Source: The American Journal of Obstetrics and Gynecology (AJOG)
Since 2015, arthropod-borne viruses (arboviruses) have spread across the Americas causing outbreaks. These outbreaks have been accompanied by increases in immune-mediated and infectious neurological diseases. Patients with Guillain-Barré syndrome who had chikungunya dual infection had more aggressive diseases.
Source: The Lancet
New techniques are needed to identify what types of interventions work best for whom to prevent behavioral problems. The current investigation applies a latent class modeling structure to identify characteristics that interrelatedly predict responses to a brief administration of Positive Adolescent Choices Training.
Source: Springer Link
Main outcome was the mean visual acuity change at 2 years. DME development was more frequent. One eye in the ranibizumab group vs the PRP group, and the other in the fourth eye.
Source: National Library Of Medicine
Cutaneous squamous cell carcinoma is the second most common type of skin cancer. Only 2% to 5% of SCCs metastasize. immunohistochemistry is widely used by pathologists to characterize skin cancers.
Source: Dermatologic Surgery
The coronavirus disease- 2019 (COVID-19) pandemic has affected patients with ST-segment elevation myocardial infarction. In-hospital mortality was higher during the pandemic, however this varied with factors such as geographical location and income status of a country.
Source: National Library Of Medicine
Study: 293 patients were treated for a traumatic injury during the months of January and July 2016. Of these 241 patients, 157 were requested to return for additional clinical care. Clinical care had been completed in 18% of patients prior to one year.
We analyzed the readability of written transcripts for the first 100 YouTube videos about "Pelvic Organ Prolapse" High quality transcripts that discuss the benefits, risk, alternative treatments, and quality of life had a median readability score of 12.5.
Source: Urology
The study aimed to estimate the inappropriate rate of UGI endoscopies in different countries. Data of 23 studies with a total of 53,392 patients were included. UGI indications were overall inappropriate in 21.7% (95% CI = 21.4-22.1) of the patients.
Source: National Library Of Medicine
The aim of the study was to evaluate the safety of non-anesthesia providers (NAPP) administered propofol sedation in patients undergoing non-advanced gastrointestinal (GI) endoscopic procedures.
Source: National Library Of Medicine
Several algorithms predicting outcomes in acute gastrointestinal bleeding have been developed over the past three decades. The aim of the current study was to compare their predictive performance and methodological quality in gastrointestinal bleeding.
Source: National Library Of Medicine
Procedure report reduced post-procedure anxiety and improved recall of findings and recommendations. Satisfaction was very high for all patients and was unaffected by receipt of a report.
Source: National Library Of Medicine
The study investigated whether a simplified clinical score could predict endoscopic findings in upper gastrointestinal bleeding (UGIB) patients. Patients were stratified according to a simple clinical score (T-score), including T1 (high-risk), T2 (intermediate-risk), and T3 (low-risk).
Source: National Library Of Medicine
Lidocaine gel and spray combination is the most ideal pharyngeal anesthesia to ensure the adaptation of the patient to the procedure. Anesthetization and compliance to procedure scores were higher and anxiety scores were lower in Group 3 than in other groups.
Source: National Library Of Medicine
Symptom-based surveys suggest that the prevalence of gastrointestinal diseases is lower in China than in Western countries. The aim of this study was to validate a methodology for the epidemiological investigation of gastrointestinal symptoms and endoscopic findings in China.
Source: National Library Of Medicine
After conventional endoscopy, the cause of anemia remains unknown in up to 40% of patients. This study involved 189 patients with IDA, including 98 women and 91 men; mean (±standard deviation) age 68 years±16.6 years. Endoscopy results were positive in 144 of 189 patients (76.2%). CT-enteroclysis and VCE allowed a diagnosis in 37 of 45endoscopy-negative patients.
Source: National Library Of Medicine
There is little consensus on whether or not hyaluronate solution (HS) is beneficial for patients. Four randomized control clinical trials (585 patients) were included into the review analyses.
Source: National Library Of Medicine
Add benzydamine (B) spray to standard treatment with a lidocaine (L) spray before upper gastrointestinal endoscopy. 118 adult patients undergoing outpatient UGE were randomly assigned to receive L (n=44), LB (38) or B (n =36) before the procedure.
Source: National Library Of Medicine
A new quantifying reagent for detecting SARS-CoV-2 antigen was developed for early and accurate detection. The sensitivity and specificity of the test were 75.7% (56/74) and 96.0% (192/200) The concordance rate in the positive group between the antigen and nucleic acid tests was 66% (66/100) It may be useful in both clinical diagnosis and in screening because it does not require special methods such as PCR.
Source: National Library Of Medicine
In the coronavirus disease 2019 pandemic, a minority of index cases are associated with a majority of secondary cases suggesting that superspreaders could drive the pandemic. Of the 11 564 samples tested, 1319 (11.4%) were positive for SARS-CoV-2.
Source: National Library Of Medicine
The study looked at children tested for SARS-CoV-2 by reverse transcription (RT) polymerase chain reaction (PCR) and immunoglobulin G antibody. Median duration of viral shedding (RT-PCR positivity) was 19.5 days. The median time to reach adequate levels of neutralizing antibodies was 36 days.
Source: National Library Of Medicine
10 patients and 7 staff members with SARS-CoV-2 infection. Thirty percent of patients remained asymptomatic over the course of infection. Cough and fever were the most common symptoms.
Source: National Library Of Medicine
Comes during the first week of its symptoms during the pandemic. Some studies have demonstrated a significant number of false-negative RT-PCR tests. It is the current gold standard diagnostic test for this virus and has sensitivity of 60-70%. The QUADAS 2 tool was used for methodological quality evaluation.
Source: National Library Of Medicine
TEDDYNoE (Task-force in Europe for Drug Development for the Young) proposes the integration of international human rights law to develop coherent ethical recommendations on pediatric research at the European level.
Source: National Library of Medicine
Data cited in this review were obtained mainly from PubMed and Medline in English from 1999 to 2013. A larger radiation field and a higher radiation dose are not always better. Effectiveness of radiotherapy combined with molecular targeted therapy needs more data to verify.
Source: National Library Of Medicine
A cross-sectional study was performed in Spanish rheumatology departments. Results were based on surveys administered to nurses. 56% of the professionals had gained their experience in outpatient clinics, 35% in day hospitals, and 9% in inpatient and primary care
Source: National Library of Medicine
The activation of NAD+-dependent deacetylase, Sirt1, by the administration of nicotinamide mononucleotide (NMN) ameliorates various aging-related diseases. Short-term NMN treatment mitigated mesangium expansion and foot process effacement. It also increased kidney concentrations of NAD+ and increased expression of Sirt1 and nicotinamide phosphoribosyltransferase (Nampt). Short-term NMN treatment in early-stage DN has remote renal protective effects.
Source: Journal of the American Society
There is a global tendency for parents to conceive children later in life. The review suggests promising avenues of research such as introducing the voice of fathers of advanced age into the research agenda. Results show that the field of APA is still in the making and that evidence is lacking to fully address the issues of APA.
Source: Oxford Academy
Time to onset of disability progression was confirmed with four measures and time to requiring a wheelchair was also analyzed. At the study end, the percentage change from baseline was lower in those who initiated oc Relzumab early than in those initially receiving placebo. But progression remains an important unmet need in multiple sclerosis.
Source: The Lancet
Multilevel models were used to assess trajectories of symptom clusters in male veterans. Growth models showed reductions in intrusions, avoidance, negative cognition/mood, and arousal/reactivity.
Source: Springer Link
Study compared intravitreal aflibercept injection (IAI) with rescue photodynamic therapy (PDT) Improvement in visual and/or functional outcomes was achieved in more than 85% of participants who were treated with IAI.
Source: National Library Of Medicine
Most eyelid defects after Mohs micrographic surgery are referred to as oculoplastic surgery or plastic surgery. 80% of patients were men, with a mean age of 74.1 years old.
Source: Dermatologic Surgery
8.9% sustained all grade cardiotoxicity, while 4.4% sustained high-grade cardiotoxicity with carfilzomib. All-grade hypertension was present in 13.2% of patients. No difference in the event rate between newly diagnosed multiple myeloma patients and those with relapsed/refractory cancer.
Source: National Library Of Medicine
Previous gait studies have shown functional improvement for up to 4 years following total ankle arthroplasty (TAA) There are no published studies assessing function at 5 years following TAA.
Dorsal lumpectomy (DL) was found to be safe and effective compared to laparoscopic (LN) nephrectomy in patients with end-stage renal disease (ESRD) DL had a shorter total OR time (173min vs 198min) and surgery time (101min vs 135min) compared to LN.
Source: Urology
Ten studies involving a total of 301 patients were included in the analysis. The pooled enteroscopy, diagnostic, and therapeutic success rates were 89.75% [95% confidence interval (CI): 79.65-94.30%]. The incidence of DBE-ERCP-related complications was 6.27% (95% CI: 2.61-11.38%)
Source: National Library Of Medicine
55 patients were randomized to meperidine and 56 to fentanyl. Total procedure time was shorter for those receiving fentanyl (mean = 87.7 min) than those receiving Meperidine.
Source: National Library Of Medicine
Capsule endoscopy has a higher yield than push enteroscopy and enteroclysis in patients with known Crohn's disease when the small-bowel mucosal disease is suspected.
Source: National Library Of Medicine
optimal sequence of procedures for same-day bidirectional endoscopy has not been established. Difficult cecal intubation increased specifically in women, in patients aged 55 years and over, patients with poor bowel preparation, and in patients who had undergone previous abdominal surgery.
Source: National Library Of Medicine
Aim: To assess the endovascular treatment of non-variceal upper gastrointestinal hemorrhage. The technical and clinical success of embolization ranged from 52-100% and 44-100%.
Source: National Library Of Medicine
Simethicone is used to increase the small bowel visualization quality (SBVQ), completion rate, gastric transit time, small bowel transit time and diagnostic yield. It decreases air bubbles in the colonic lumen, but does not improve bowel preparation.
Source: National Library Of Medicine
Capsule endoscopy is a valuable tool in the diagnostic evaluation of obscure gastrointestinal bleeding. A potential small intestinal bleeding source was found in 60% of the patients when all the studies were combined. Some patients did not have a source of bleeding in the small intestine.
Source: National Library Of Medicine
Objective: To observe the lower gastrointestinal mesenchymal tumors CT virtual endoscopy and pathology. Methods: Select 80 patients suspected colon gastroenterology treat in the hospital gastroenterologist department.
Source: National Library Of Medicine
When magnification was added to CE, the detection rate of patients with dysplasia and dysplastic lesions improved. It is thus necessary to use CE in the surveillance of Dysplasia in patients with IBD in clinical practice, authors say.
Source: National Library Of Medicine
Reviewing wireless capsule endoscopy recordings by a physician is time-consuming and laborious. The study evaluated the efficacy of a nurse in interpreting WCE recordings. Nurse's mean capsule reading time was significantly longer for the nurse compared with the gastroenterologist.
Source: National Library Of Medicine
Authors: 9 women were positive for SARS-CoV-2 in nasopharyngeal samples and 13 presented positive specific antibodies of the coronavirus. Vaginal delivery occurred in 94% of the cases and only 6% underwent a cesarean section, always for obstetric reasons. No fetal transmission was observed and maternal and neonatal prognosis was excellent.
Source: National Library Of Medicine
The nCoV19 CDC includes two targets for detecting SARS-CoV-2 and an RNaseP (RP) and an RNA extraction quality control. Several RT-qPCR kits are available for SARS and some have emergency use from the US Food and Drug Administration. Only one set of DNA is required for each sample to be tested.
Source: National Library Of Medicine
Convalescent plasma is undergoing randomized trials as a potential therapeutic option for COVID-19 infection. Clearance for donation required successful completion of an online questionnaire and an in-person screening visit. After receiving 3093 online questionnaires, 521 individuals presented for in-person screening visits, with 40.1% (n = 209) fully qualifying.
Source: National Library Of Medicine
The mobile laboratory was equipped with a 6-axis robot arm for automated oropharyngeal swab specimen collection. The virus in the collected specimen was inactivated rapidly using an infrared heating module
Source: National Library Of Medicine
3DP swabs have been used to mitigate swab shortages during the coronavirus disease 2019 (COVID-19) pandemic. Clinical validation for diagnostic accuracy and consistency and patient acceptability is crucial to evaluate the swab's performance.
Source: National Library Of Medicine
Results of SARS-CoV-2 specific real-time reverse transcription (RT) are used for initial diagnosis and follow-up of Covid-19 patients and asymptomatic virus carriers. Clinical decision-making and health management policies often are based additionally on cycle threshold ( Ct) values to guide patient care. This study highlights the limitations of interpreting Ct values from the various SARS.-CoV genome detection protocols.
Source: National Library Of Medicine
The coronavirus disease 2019 (COVID-19) pandemic has posed significant challenges globally. This review aimed to identify and describe possible vaccines for the prevention of the pandemic. A total of 141 vaccines in development against SARS-CoV-2 were identified. So far, 13 vaccines (9.2%) are under clinical evaluation.
Source: National Library Of Medicine
Objectives: The increase in the number of patients with coronavirus disease 2019 (COVID-19) has delayed real-time reverse transcription-quantitative polymerase chain reaction (RT-qPCR), requiring proper shipping and storage conditions. Study aims to assess how some conditions, such as storage period, temperature, media or buffer, and sample types, affect the results of acute respiratory syndrome.
Source: National Library Of Medicine
First cases of SARS-CoV-2 infection were recorded in Ghana on March 12, 2020. The highest number of cases were reported in June when the GHS embarked on targeted contact tracing. From February 3 to August 21, the NMIMR processed 283 946 (10%) samples. Test results are now provided within 24 to 48 hours of sample submission enabling more effective response and containment.
Source: National Library Of Medicine
A key question concerning coronavirus disease 2019 (COVID-19) is how effective and long-lasting immunity is in individuals who were previously infected with SARS-CoV-2. We aimed to evaluate the risk of SARS.-Cov-2 re-infections in the general population in Austria.
Source: National Library Of Medicine
In many European countries, pediatric junior staff has no formal training in adolescent medicine. This position paper proposes a set of competency-based training goals and objectives.
Source: National Library of Medicine
12 expert radiation oncologists contoured the liver, esophagus, gastroesophageal junction (GEJ), stomach, duodenum, and common bile duct (CBD) Contours were overlaid and compared for agreement using MATLAB.
Source: National Library Of Medicine
38% of Spanish rheumatologists are working in private practice. Catalonia has the most private practice doctors, followed by Madrid, Andalusia, and Valencia. The average private practice professional is 49 years old with a working day of 42 hours a week.
Source: National Library of Medicine
Hemoglobin vesicles have been developed as artificial oxygen carriers. They have the potential to serve as a substitute for red blood cell transfusion. In a study, rabbits received isovolemic fluid resuscitation with an equivalent volume of hemorrhage every 5 minutes. Hemoglobin vesicle infusion may be effective in the initial management of massive obstetric hemorrhage.
Source: The American Journal of Obstetrics and Gynecology (AJOG)
Fears of negative self-portrayal are strongly associated with safety behaviour use in SAD. Fears of receiving compassion could motivate those with SAD to engage in safety behaviours to keep others at a distance. The implications of our findings for addressing safety behaviours in the treatment of SAD are discussed.
Source: Springer Link
The study evaluated vascular characteristics of the choriocapillaris in eyes with Pachychoroid. Eyes with pachychoroid disease were defined as those with a history of central serous chorioretinopathy or peripapillary pachyChoroid syndrome. Eyes without disease were defined as eyes with no history of disease with a subfoveal choroidal thickness. Branch per square millimeter was fewer in pachyhoid disease eyes as compared with normal controls. ChoriocAPillaris vascular parameters suggest that pach
The MSDO standardized letter of recommendation (SLOR) was created to improve the efficiency, validity, and stratification of applicants to dermatology fellowship training programs. Grade inflation and limited variability in scores were evident.
Source: Dermatologic Surgery
ICD therapy decreased all-cause mortality in comparison to optimal pharmacological treatment. Findings significantly affected the daily practice of ICD implantation in Europe.
Source: National Library Of Medicine
Surgeons are influenced by radiographic deformity but do not agree on adequate alignment after reduction. satisfaction with reduction was fair and there was no evidence of significant variation
A questionnaire regarding IVM participation was distributed to Societies for Pediatric Urology members (SPU), pediatric urology fellows (PUFs), and pediatric urologic fellowship program directors (PDs) Results in 98 of 733 SPU members queried responded; 62/98 (63%) having volunteered.
Source: Urology
Healthcare workers are at increased risk of SARS-CoV-2 infection from both patients and other HCW with coronavirus disease 2019 (COVID-19) First 7-9 days of symptoms are associated with enhanced infectivity.
Source: National Library Of Medicine
Accurate rapid diagnostic tests for SARS-CoV-2 infection could contribute to clinical and public health strategies to manage the pandemic. Point-of-care antigen and molecular tests to detect current infection could increase access to testing and early confirmation of cases. We present sensitivity and specificity with 95% confidence intervals (CIs) for each test and pooled data using the bivariate model for antigen and Molecular-based tests. We tabulated results by test manufacturer and complianc
Source: National Library Of Medicine
Evidence for vertical transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is not well established. Of 336 newborns screened for COVID-19, only 15 were positive for throat swab RT-PCR. Of those 15, only five neonates were delivered by cesarean section. There is not enough evidence on vertical virologic transmission of Covid-19 infection during the third trimester of pregnancy. Further research involving an adequate sample size of breast milk, placenta, amniotic fluid, and
Source: National Library Of Medicine
accurate virus detection plays a crucial role in the current public health crisis. Quantitative real-time reverse transcriptase-polymerase chain reaction (RT-qPCR) kits have been reliably used for detection of SARS-CoV-2 RNA since the beginning of the outbreak. This is the first comparative study to evaluate CPA and RT-q PCR kits' specificity and sensitivity for Sars-Cov-2 detection. It could serve as a reference for clinical laboratories, thus informing testing protocols.
Source: National Library Of Medicine
Our first aim was to determine both the infection status and seroprevalence of SARS-CoV-2 in health workers. Second aim to evaluate the occupational and demographic predictors of seropositivity. We invited 713 staff members at 24 out of 35 health facilities in the City of Bulawayo in Zimbabwe. Of the 635 people (aged 18-73) providing a blood sample 39.1% reported a history of past COVID-19 symptoms while 14.2% reported having current symptoms.
Source: National Library Of Medicine
SARS-CoV-2 is a pandemic virus and the etiologic agent of coronavirus disease 2019 (COVID-19) Clinical testing for antibodies to the virus has rapidly become widespread. The College of American Pathologists developed a new proficiency testing survey for anti-SARS -CoV -2 antibody assays. Results were analyzed for agreement by immunoglobulin (Ig) isotype tested, assay manufacturer, and methodology.
Source: National Library Of Medicine
NAbs are capable of binding to a virus to render it incapable of infection. The ability of commercially available SARS-CoV-2 serological tests to detect NAbs has not been widely reported. We sought to correlate the antibodies detected by an automated chemiluminescent immunoassay with NAbs. NAbs were detected in 66% (23/35) of the antibody-positive samples.
Source: National Library Of Medicine
In the SARS-CoV-2 pandemic reagents and utensils for NA purification have been in short supply. This has generated interest in methods that eliminate the need for NA Purification. IGEPAL-CA-630 (IGEPAL) was added to SARS.-Cov-2 MM to 0.3% final concentration and the crude sample was added directly to the. DNA well containing MM. All 30 previously test negative samples remained negative when tested in in-well lysis, direct rRT-PCR.
Source: National Library Of Medicine
Antigen tests can provide timely results, which is of particular importance in a primary care setting. Most tests had a sufficient sensitivity to identify symptomatic subjects infected with SARS-CoV-2 and with transmissible infection. Newly introduced antigen tests need to be validated in a clinical setting to define their clinical usefulness. One test investigated had a poor clinical performance.
Source: National Library Of Medicine
Serologic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has experienced a changing landscape of available assays, with uncertainty surrounding performance characteristics. Studies are needed to directly compare multiple commercially available serology assays. The specificity and sensitivity achieved by the Roche and Siemens assays would be acceptable for testing in lower-prevalence regions and have the potential of orthogonal testing advantages if used in combination.
Source: National Library Of Medicine
The gap in perceived competency in physician-related radiotherapy tasks may be caused by the complex interaction of clinical processes, people, and technology.
Source: National Library Of Medicine
An epidemiological questionnaire was sent to all rheumatologists. Eight hospitals were accredited by the National Commission to develop a training program in Rheumatology. There were 7 hospitals without a rheumatologist in the public health sector. There has been an increase of 4.8% in the last seven years.
Source: National Library of Medicine
Complex Posttraumatic Stress Disorder (CPTSD) was included in the 11th revision of the International Classification of Diseases (ICD-11) We investigated whether CPTSD predicted and moderated treatment outcomes of PE, intensified PE, and Skills Training in Affective and Interpersonal Regulation.
Source: Springer Link
Cervical cancer screening and follow-up data among 363,546 women enrolled in the CDC's National Breast and Cervical Cancer Early Detection Program. Women who were never screened or who were not screened had greater immediate risks.
Source: The American Journal of Obstetrics and Gynecology (AJOG)
To compare the visibility and diagnostic performance of NBI endoscopy. NBI should be used to improve the performance of the stomach to detect intestinal metaplasia. Pronase premedication was not different in either group compared with that of white light endoscopes.
Source: National Library Of Medicine
Carbon dioxide (CO(2) has been proposed as an alternative to room air for GI endoscopy. The study was conducted to assess the safety and efficacy of CO( 2) insufflation. Data from RCTs, as well as from nonrandomized studies, were extracted to make the findings.
Source: National Library Of Medicine
Structural-enhancement (SE) function electronically improves the video-endoscopic signal of Olympus processors (EXERA CV-160 or greater) This is the first study comparing SE with or without it during upper digestive endoscopy and colonoscopy.
Source: National Library Of Medicine
Eighty patients undergoing diagnostic esophagogastroduodenoscopy in a tertiary care medical center were randomized to either lidocaine swab or spray.
Source: National Library Of Medicine
No ideal scheme is available to study the protocol with midazolam and ketamine used by anesthetists at our institution. The starting ketamine dose was increased until the appropriate dissociative state was reached. The sedation protocol with ketamine is safe and efficient.
Source: National Library Of Medicine
Patients in the verbal information group responded more accurately to the questions related to the procedure. These patients experienced less pain, breathing difficulties and regret.
Source: National Library Of Medicine
Capsule endoscopy identified small intestinal bleeding sites beyond the range of push enteroscopy. A bleeding site was found in 11 of 20 patients during capsule endoscopic.
Source: National Library Of Medicine
Objective: Previous studies show conflicting results in the diagnostic yield of oesophagogastroduodenoscopy (OGD) and colonoscopy in identifying potential bleeding sources (PBS) in patients investigated for occult gastrointestinal bleeding (OGIB)
Source: National Library Of Medicine
Doctors are probably more cost-effective than nurses for plausible values of a QALY. Patients in the doctor group gained 0.015 QALY more than those in the nurse group, at an increased cost of about pound56 (euro59, $78) per patient.
Source: National Library Of Medicine
Erythromycin, a motilin agonist, induces gastric emptying in patients with variceal bleeding. The need for repeat endoscopy and the mean number of units of blood transfused did not differ significantly in the 2 groups.
Source: National Library Of Medicine
A 40-year-old pregnant woman with no previous complications presented a late miscarriage at 16 weeks of gestation on day 9 of COVID-19 disease. The results of her nasopharyngeal swab for SARS-CoV-2, tested the same day, were negative.
Source: National Library Of Medicine
SARS-CoV-2-infected subjects have been proven contagious in the symptomatic, pre-symptomatic, and asymptomatic phases. The identification of these patients is crucial in order to prevent virus circulation. No reliable data on the sensitivity of nasopharyngeal swabs (NPS) are available. Three hundred and ninety-three NPS were evaluated in 233 patients; the sensitivity was 77% (95% CI, 73 to 81%)
Source: National Library Of Medicine
To overcome the challenge of nucleic acid (NA) extraction and testing kit availability, an efficient method is urgently needed. The standard reverse transcriptase chain reaction (RT-PCR) test of the SARS CoV-2 was employed targeting the nucleocapsid (N) and open reading frame (ORF1ab) We found that a single positive sample can be amplified and detected in pools of up to 7 samples depending on the cycle threshold.
Source: National Library Of Medicine
The best direct methods detected 10 fold fewer viruses than indirect methods. With extracted RNA, the BGI RT-qPCR detection system exhibited superior performance over the Norgen system. The BGI detection system is more expensive than other options tested here.
Source: National Library Of Medicine
Interest in global health has risen among medical students applying to and residents training in radiation oncology, often outpacing available educational offerings.
Source: National Library Of Medicine
A multidisciplinary task force, representing 10 European countries, formulated a definition for PE and 10 research questions that guided a systematic literature review (SLR) Eight recommendations were developed, four with strength A evidence.
Source: National Library of Medicine
Improving child and adolescent mental health (CAMH) is a priority worldwide. The majority of children with psychiatric conditions in low-middle-income countries (LMIC), like Ghana, receive no treatment due largely to limited resources and few CAMH training opportunities.
Source: National Library of Medicine
Bioresorbable scaffolds (BRS) considered being beneficial for coronary bifurcation lesions. A high rate of scaffold thrombosis remains of concern.
Source: National Library Of Medicine
Many patients have hip dysplasia with progressive medial flattening of the femoral head. This is the first study to quantify the effect of hip surgery on the sphericity of femoral heads.
Review of 3,101 men presenting for initial fertility evaluation at a tertiary care, academic health system between 1999 and 2018. The overall prevalence of prolactinoma was 35-fold higher than the prevalence in the general male population.
Source: Urology
Reliable closure is a prerequisite for conventional and innovative endoscopic procedures, such as NOTES. OTSC System is a safe and effective method for endoscopic closure of gastrointestinal perforations and acute anastomotic leaks by means of the over-the-scope-clip system.
Source: National Library Of Medicine
Capsule recordings were blindly read by three endoscopists. The average esophageal transit time of the capsule was 361 +/- 393 seconds. No adverse event was observed after either EGD or capsule endoscopy.
Source: National Library Of Medicine
Obscure small-bowel disorders are jejunal and ileal lesions undiagnosed by traditional imaging techniques. We evaluated the diagnostic usefulness and safety of capsule endoscopy for these disorders in children and adolescents.
Source: National Library Of Medicine
Reports on the performance of unsedated ultrathin endoscopy via the transnasal (uTNE) and transoral (uTOE) routes are conflicting. We aimed to estimate the technical success rate, patient preference, and acceptability of uTNE and uTOE alone and in comparison with conventional EGD (cEGD) Thirty-four studies met the inclusion criteria with 6659 patients in total.
Source: National Library Of Medicine
Many patients with upper gastrointestinal (GI) bleeding have a benign outcome and could receive less intensive and costly care if accurately identified. Early endoscopy performed shortly after admission in the emergency department safely triaged 46% of patients with nonvariceal upper GI bleeding to outpatient care.
Source: National Library Of Medicine
Little is known how to most effectively deliver relevant information to patients scheduled for endoscopy. We designed a prospective study in two Swiss teaching hospitals. Written information led to more favorable assessments of the quality of the information.
Source: National Library Of Medicine
Study focused on the nature and frequency of symptomatic and asymptomatic SARS-CoV-2 infection. A sample of 4778 adults from New Orleans and Baton Rouge, Louisiana were given a survey of symptoms and co-morbidities
Source: National Library Of Medicine
Children infected with SARS-CoV-2 are more likely to have mild symptoms and are at a lower risk of developing the severe respiratory disease compared with adults. It remains unknown how the immune response in children differs from that of adolescents and adults.
Source: National Library Of Medicine
Covert severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections could be seeding new outbreaks. To explore the roles of immunoglobulin M (IgM) and immunoglobulin G (IG) antibodies detection, nucleic acid tests, and computed tomography (CT) scanning to identify asymptomatic SARS- CoV- 2 infection
Source: National Library Of Medicine
SARS-CoV-2 is the reference laboratory method to diagnose the disease. The sensitivity of Panbio COVID-19 Ag Rapid Test Device is lower in children than in adults. However, considering the good values of specificity, negative and positive predictive values this test could be used as a frontline test to obtain quick results.
Source: National Library Of Medicine
Study evaluated Sofia, Standard Q and Panbio™ rapid antigen detection tests. All three tests reached more than 90% sensitivity for samples with a high viral load. The RADTs were less sensitive than RT-PCR but benefit from the speed and ease of testing. Repeated testing in appropriate settings may improve the overall performance.
Source: National Library Of Medicine
Interest in global health has risen among medical students applying to and residents training in radiation oncology, often outpacing available educational offerings.
Source: National Library Of Medicine
89.1% of trainees decide specialty during senior house officer experience. Early postgraduate experience is key to the choice of specialty. Concerns over the future place of rheumatology in primary vs secondary care.
Source: National Library of Medicine
Children and those with a history of therapy were more likely to make initial contact. The markers of clinical need included PSC-35 Global Scores and the number of psychiatric diagnoses.
Source: National Library of Medicine
There is no consensus on whether CF-LVAD as a bridge or destination therapy can equal orthotopic heart transplantation. Mortality at different time points and adverse events were analyzed.
Source: National Library Of Medicine
Outpatient total joint arthroplasty does not appear to be a risk factor for new opioid dependence. Findings support the continued transition to the outpatient-TJA model for lower-risk patients, authors say.
Webinar curriculum of fundamental reconstructive urology topics. Survey responses showed >50% of practices offer reconstructive Urologic services. All participants rated the topics presented as relevant to their education/practice
Source: Urology
High-dose pharyngeal anesthesia reduces patient discomfort during unsedated upper gastrointestinal endoscopy. However, apprehensive patients and younger patients reported relatively high levels of discomfort.
Source: National Library Of Medicine
The A-Line auditory evoked potential index (AAI) is a newly developed composite parameter representing the degree of hypnosis. We explored the performance and validity of the AAI during conventional sedation for gastrointestinal (GI) endoscopy.
Source: National Library Of Medicine
Knowledge of quality measures in endoscopy among trainees is unknown. We tested the knowledge of endoscopic-related quality indicators among U.S. trainees. We found that knowledge of these indicators can improve with a Web-based tutorial.
Source: National Library Of Medicine
Wireless capsule endoscopy and double-balloon enteroscopy are new diagnostic methods. We compared the clinical efficacy of CE and DBE. CE revealed abnormal findings in 29 (90.6%) of 32 patients.
Source: National Library Of Medicine
Pain at the injection site, fatigue, headache, myalgias, arthralgias, chills, and fever can be early indicators of an increased need for glucocorticoid replacement in patients with adrenal insufficiency. The Pituitary Society surveyed its membership to understand planned approaches to glucoc Corticoid management in patients who will receive a COVID-19 vaccine.
Source: National Library Of Medicine
World Health Organization declared COVID-19 a global health emergency on January 30, 2020. By December 2020, the safety and efficacy of the first vaccines were demonstrated. Twitter polling system has provided a viable method for gaining rapid, large-scale, international public health insights on highly relevant and timely SARS-CoV-2-related topics. Since people's perceptions and views are strongly influenced by social media, the snapshots provided by these media platforms represent a static ima
Source: National Library Of Medicine
The 11th KAIMRC Annual Research Forum Themed "COVID-19 Vaccine: Global Challenges and Prospects Forum" discussed COVID19 Vaccines. The Forum was held to shed light on these vaccines as many are at the late stage of Phase III clinical trials and ready to be marketed.
Source: National Library Of Medicine
The 11th KAIMRC Annual Research Forum Themed "COVID-19 Vaccine: Global Challenges and Prospects Forum" discussed COVID19 Vaccines. The Forum was held to shed light on these vaccines as many are at the late stage of Phase III clinical trials and ready to be marketed.
Source: National Library Of Medicine
Vaccine hesitancy has become a growing concern globally. It calls into question the safety and efficacy of vaccines. It threatens the progress made in combating morbidity and mortality including efforts to introduce COVID-19 vaccines.Recommendations include strengthen social listening and digital engagement to address the concerns of caregivers and healthcare professionals.
Concerns have been expressed about the association of soft tissue filler injections and the COVID-19 vaccines. The International Society for Dermatologic and Aesthetic Surgery understands these concerns. The data collected does not support the concern for an increased risk of developing adverse reactions following soft tissue. filler injections associated with the CoVid vaccines compared to that risk associated with other previously described triggers or the default risk. J Drugs Dermatol. 20(4)
Source: National Library Of Medicine
Vaccines have been developed in unprecedented time and quantifying levels of hesitancy towards vaccination among the general population is of importance.
Source: National Library Of Medicine
The achievements of vaccine research and development bring a hope to our societies that we may cope with the COVID-19 pandemic. There are two aspects that should be maintained in balance: the immediate necessity for vaccine research, and the need for protection of research subjects.
Source: National Library Of Medicine
Pfizer-BioNTech COVID-19 vaccine has reported 4,393 (0.2%) adverse events in the Cases of anaphylaxis were determined to be rare but still under investigation. The median interval from vaccine receipt to symptom onset was 13 minutes.
Source: National Library Of Medicine
SARS-CoV-2 is a new type of coronavirus that causes the Coronavirus Disease 2019 (COVID-19). It has been the most challenging pandemic in this century. An effective vaccine is urgently needed to control this pandemic. Key takeaways from previous vaccination studies of SARS and MERS-CoVs. Finally, based on these prior vaccination experiences, we discuss recent progress and potential challenges of COVID-19 vaccine development.
Source: National Library Of Medicine
Several coronavirus disease 2019 (COVID-19) vaccines are currently in human trials. 71.5% of participants reported that they would be very or somewhat likely to take a vaccine, and 48.1% reported accepting their employer's recommendation. Differences in acceptance rates ranged from almost 90% (in China) to less than 55%. Respondents reporting higher levels of trust in information from government sources were more likely to accept a vaccine.
Source: National Library Of Medicine
Study attempts to understand coronavirus disease 2019 (COVID-19) vaccine demand and hesitancy. The majority reported a probably yes intent (54.6%) followed by a definite yes intention (28.7%).The findings demonstrate the utility of HBM constructs in understanding COVID-19 vaccination intent and WTP. It is important to improve health promotion and reduce the barriers to COVID 19 vaccination.
Source: National Library Of Medicine
The Coronavirus disease 2019 (COVID-19) has spread to almost all nooks and corners of the world. Medications are being developed to target the spike, membrane, nucleocapsid or envelope proteins. The spike protein is also a critical target for vaccine development. Even though mRNA and DNA vaccines are being designed and moved into clinical trials, these types of vaccines are yet to be approved by regulatory bodies for human use. This review focuses on the drugs and vaccines being developed agains
Source: National Library Of Medicine
Helicobacter pylori testing has been suggested as an alternative to endoscopy for young patients with dyspepsia. Study in Gloucestershire found a significant reduction in referrals for endoscope in the intervention group compared to the control group
Source: National Library Of Medicine
The ideal effect-site concentration (Ce) of propofol has not yet been defined in an Asian population. This study aimed to determine the ideal Ce of Propofol in painless gastrointestinal endoscopy in a Taiwanese population.
Source: National Library Of Medicine
Study aims were to review pathology of GI tract in children with acalculous biliary-type abdominal pain and to evaluate the pain improvement after a 2-week trial of proton pump inhibitor (PPI) and laparoscopic cholecystectomy (LC) Four of ten children experienced a complete response to PPIs and did not require LC.
Source: National Library Of Medicine
To investigate, researchers looked at the link between the behavior of Barrett's patients and the treatment they received from the hospital. They compared the treatment with the behavior in response to the treatment of those who were subjected to it
Source: National Library Of Medicine
Capsule recordings were blindly read by two endoscopists. Indication for a new prophylactic treatment and patient satisfaction were determined for both procedures.
Source: National Library Of Medicine
Bispectral index (BIS) monitoring has been used as an objective measurement tool for sedation depth. Results of several studies evaluating the benefits of BIS monitoring for gastrointestinal endoscopy were not consistent.
Source: National Library Of Medicine
optimal sequence of procedures for same-day bidirectional endoscopy using moderate sedation has not been established. Patient's discomfort and satisfaction, as expressed by the amount of analgesia added to sustain conscious sedation, and the postprocedure satisfaction reported by the patients were set as primary outcomes.
Source: National Library Of Medicine
An effective bowel cleanse can improve the imaging quality of video capsule endoscopy (VCE) We compared the efficacy of 4 L of clear liquids, 2 L of polyethylene glycol (PEG), and 4 L. of PEG on the image quality of VCE.
Source: National Library Of Medicine
Carvedilol was more efficacious than traditional NSBBs in decreasing the variceal rebleeding rate [odds ratio (OR): 0.75; 95% confidence interval (CI: 0.38-0.75, P = 0.0003), lowering the degree of esophageal varices (OR: 4.40, 95% CI: 2.64, P < 0.00001) No difference was noted between carvedilol and traditional NS BBs with respect to mortality and heart rate.
Source: National Library Of Medicine
Comes to town of Waukesha, Wisconsin, where the town's goal is to get the city to get back on track. The town's history is riddled with controversy, but this town is trying to make amends with the city.
Source: National Library Of Medicine
The SARS-CoV-2 virus has infected more than 49 million people causing more than 1.2 million deaths worldwide since its emergence from Wuhan, China in December 2019. Tuberculosis is also a major infectious respiratory disease of the worldwide prevalence and vaccine development for tuberculosis has been ongoing for decades. we highlight some of the common features, challenges, and complications in tuberculosis vaccine development, which may also be relevant for, and inform COVID-19 vaccine develop
Source: National Library Of Medicine
The development of a vaccine against SARS coronavirus 2 (SARS-CoV-2) will be the way to restore normality to civil life in this time of a devastating pandemic. As of mid-August 2020, more than 20 million people have been infected and more than 760 000 lives have been lost worldwide. There are many vaccine candidates in development, including preclinical and clinical testing.
Source: National Library Of Medicine
A significant portion of the U.S. population may experience vaccine hesitancy of a new COVID-19 vaccine. This poses dangers to both the individual and their community, since exposure to a contagious disease places the person at risk, and individuals are far more likely to spread the disease to others if they do not get vaccinated. Experience from the influenza vaccines has shown vaccine acceptance has not been optimal, and this new vaccine, even though it is not approved, is already showing layp
Source: National Library Of Medicine
The global effort to develop a coronavirus disease 2019 (COVID-19) vaccine is on track to produce one or more vaccines. The benefits of a vaccine will decline substantially in the event of manufacturing or deployment delays, vaccine hesitancy, or greater epidemic severity.
Source: National Library Of Medicine
The coronavirus-2 (SARS-CoV-2) has created a potentially fatal disease, coronaviruses disease-2019 (COVID-19) Despite the continuous efforts of researchers to find effective vaccines and drugs for COVID-20, there is still no success. The literature regarding the vaccine candidates currently in the clinical trials, as well as main candidates in pre-clinical stages for development and research, were reviewed. There are several limitations in the field of rapid vaccine development against SARS-CoV-
Source: National Library Of Medicine
Vaccines are urgently needed to control the coronavirus disease 2019 (COVID-19) pandemic. Several vaccine candidates are being developed, several of which have completed late-stage clinical trials and are reporting positive results. The aim is to help them return to pre-pandemic normalcy.
Source: National Library Of Medicine
The aim of the study was to predict the frequency of vaccine refusal against domestic and foreign COVID-19 vaccines. The most common reasons for refusal were anxiety about vaccine side effects, lack of knowledge about the effectiveness of vaccines, and distrust of vaccines originating from abroad. This study demonstrates that vaccine uptake can be increased by considering the higher preference for domestic vaccines.
Source: National Library Of Medicine
The availability of a COVID-19 vaccine has been heralded as the key to controlling the -19 pandemic. Success will rely on public willingness to be vaccinated, according to a new study. The study looked at how COVID-19 vaccines are developed and tested, including their safety and efficacy. It identified factors that may affect vaccine acceptability in ethnic minority and lower-income groups who are disproportionately affected by the vaccine.
Source: National Library Of Medicine
Ecuador was one of the first and most severely affected by the COVID-19 pandemic. Survey results show that a very large proportion of individuals were willing to accept a vaccine, and at least 85% of individuals would pay a positive amount. Regression results show that WTP for the vaccine was associated with income, employment status, the perceived probability of needing hospitalization if contracting the virus causing COVID-19, and region of residence.
Source: National Library Of Medicine
SARS-CoV-2, the causative agent of COVID-19, has imposed a major public health threat. Several potential candidate vaccines being rapidly developed are in clinical evaluation. Safety is a major aspect to be considered before deploying such vaccines to the public.
Source: National Library Of Medicine
Intestinal gases are currently used for the diagnosis of disorders including small intestinal bacterial overgrowth and carbohydrate malabsorption. The capsule measured >3000 times higher concentrations of hydrogen compared to breathe tests, resulting in a signal-to-noise ratio of 23.4 for the capsule compared to 4.2 for the breath test.
Source: National Library Of Medicine
100 patients with severe acute pancreatitis were randomized to receive NJTs by transnasal endoscopy or fluoroscopy. The successful placement was confirmed by an abdominal radiograph.
Source: National Library Of Medicine
Transnasal endoscopy (TNE) with ultrathin endoscopes has been advocated as an attractive alternative to SOGD. The aim was to assess tolerability, acceptability, and quality of TNE, in comparison with a standard upper endoscope.
Source: National Library Of Medicine
The benefits of routinely administered sedative medication or topical pharyngeal anesthesia are controversial. The aim of this study was to clarify their effects on patient tolerance and the difficulty of upper endoscopy.
Source: National Library Of Medicine
Helicobacter pylori "test and treat" has been recommended for the management of young dyspeptic patients without alarm symptoms. None of these trials have had a sufficient sample size to confirm that "test & treat" costs less or to detect small differences in effect.
Source: National Library Of Medicine
Researchers looked at 95 patients with obscure gastrointestinal bleeding. A suspected source of bleeding was found in 39 of 95 patients. 64% of the suspected bleeding sources were within reach of a standard endoscope
Source: National Library Of Medicine
Early endoscopy, Helicobacter pylori eradication, and empirical acid suppression are commonly used dyspepsia management strategies. 'Test and treat' was the most cost-effective strategy.
Source: National Library Of Medicine
The study compared the diagnostic yield of wireless capsule endoscopy (WCE) and enteroclysis in evaluating the extent of small-bowel involvement in Crohn's disease (CD) Abnormal findings were documented in 8 of 31 patients by using enteroclysis and in 22 of 31 cases by using WCE.
Source: National Library Of Medicine
The study evaluated the safety and efficacy of endoscopic band ligation in the management of gastroesophageal reflux disease. 150 patients with refractory GERD were assigned to an EBL group and a control group.
Source: National Library Of Medicine
Push enteroscopy (PE) is at present considered to be the most effective diagnostic procedure. In the present trial in patients with CGB, wireless CE had the highest diagnostic yield and was significantly superior to PE. Both CE and PE were safe and were not associated with any morbidity.
Source: National Library Of Medicine
The coronavirus disease 2019 (COVID-19) is caused by a novel coronovirus known as SARS-CoV-2. The rapid spread of this pathogen and the increasing number of cases highlight the urgent development of vaccines. DNA vaccination is a promising alternative to conventional vaccines.
Source: National Library Of Medicine
Radiologists should consider recent COVID-19 vaccination history as a possible differential diagnosis for patients with unilateral axillary adenopathy. Hyperplastic axillary nodes can be seen on sonography after any vaccination but are more common after a vaccine that evokes a strong immune response.
Source: National Library Of Medicine
The COVID-19 pandemic caused by SARS-CoV-2 has spread rapidly. Studies on the roles of asymptomatic and mildly infected subjects in disease transmission, use of antiviral drugs, and vaccination of the general population will be very important for mitigating the effects of the eventual return of this pandemic.There also is a need to comprehensively compile the details of previous studies on SARS-related vaccines that can be extrapolated to identify potent vaccine targets for developing COVID-19 v
Source: National Library Of Medicine
Older people and care home residents are likely to be amongst the first to be vaccinated, but these patient groups are usually excluded from clinical trials. Their safety and efficacy in older people is critical to their success. Although the speed and impact of the pandemic on older people with frailty justify an approach where they are offered vaccination first, patients and their carers and supervising health care professionals alike will need to make a decision on accepting vaccination base
Source: National Library Of Medicine
Researchers used an expanded SEIR model with social contact matrices to assess age-specific vaccine allocation strategies in India. Prioritizing COVID-19 vaccine allocation for older populations led to the greatest relative reduction in deaths. Findings support global recommendations to prioritize -19 vaccines for older age groups. Optimal vaccine allocation strategies will depend on vaccine characteristics, the strength of non-pharmaceutical interventions.
Source: National Library Of Medicine
Women and children are widely considered the most vulnerable in times of emergency, whether in war or during a pandemic. The inclusion of pregnant and lactating mothers in clinical trials for the development of vaccines is of vital importance, say the researchers. They suggest a gendered approach to ensure the specific needs of women and their newborns are considered.
Source: National Library Of Medicine
The novel coronavirus SARS-CoV-2 after emerging in China has caused a global pandemic. There are no clinical data yet suggesting that any available candidate vaccine will be effective for COVID-19. Extensive research is underway with some success in identifying monoclonal antibodies from recovered patients. In absence of a vaccine or a widely available effective therapy, quarantine and other preventive measures are essential in curtailing the risk of pandemic spread.
Source: National Library Of Medicine
Leaders must invest in evidence-based vaccine delivery strategies that generate demand, allocate and distribute vaccines, and verify coverage. There must be an understanding of the roots of vaccine hesitancy, involvement of trusted sources of authority in advocacy for vaccination, and commitment to engagement with communities. Lessons of past pandemics suggest that nations should invest in evidence-informed strategies to ensure that coronavirus disease 2019 (COVID-19) vaccines protect individual
Source: National Library Of Medicine
An efficacious COVID-19 vaccine is currently the world's leading research priority. Several nations have indicated they would be prepared to authorize emergency use or conditional approval on public health grounds if there is a compelling case for use of a vaccine before it is licensed. candidate vaccines attain emergency use designation and be programmatically deployed before their phase 3 trials conclude, such a strategy could have far reaching consequences for COVID-19 vaccine research and th
Source: National Library Of Medicine
The global desire to produce and deploy a safe and effective vaccine to protect against SARS-CoV-2 is unprecedented. The UK Vaccine Taskforce has stated that the exit strategy depends on a vaccine that is effective in reducing mortality, improving population health by reducing serious disease and protecting the NHS.
Source: National Library Of Medicine
Transnasal esophagogastroduodenoscopy (EGD) using an ultrathin endoscope is less stressful to the cardiovascular system with less elevation of systolic blood pressure (BP) than oral procedures. autonomic nervous responses were determined employing power spectral analysis (PSA) of heart-rate variations on electrocardiogram
Source: National Library Of Medicine
Continuous propofol infusion seems to be both effective and safe to achieve sedation for diagnostic upper gastrointestinal endoscopy in spontaneously breathing. Amnesia was achieved in all of the 21 patients older than 4 years. Adverse effects observed consisted of 1 patient vomiting.
Source: National Library Of Medicine
Given M2A wireless video capsule (Given Imaging Ltd., Yoqneam, Israel) endoscopy was compared to barium follow-through. Barium study was considered diagnostic in 4 (20%) patients
Source: National Library Of Medicine
Study evaluated feasibility of intubation under video laryngoscopic guidance in the left lateral position during upper gastrointestinal endoscopic surgery. Results showed no difference in terms of time required for intubating (Group L, 23.95 ± 4.43 seconds and Group S, 23,.44± 4.78 seconds) However, Group S exhibited significant hemodynamic changes during shift of decubitus and severe sore throat.
Source: National Library Of Medicine
The Erlangen Active Simulator for Interventional Endoscopy (EASIE) using ex-vivo porcine organs was introduced in 1997. Study should analyze whether repeated EASIE. simulator training in endoscopic hemostasis led to superior performance compared. with a traditionally educated group.
Source: National Library Of Medicine
Confocal laser endomicroscopy is an endoscopic method that provides in vitro real-time imaging of the mucosa at a cellular level. It is the only method that enables in vitro functional assessment of intestinal barrier function.
Source: National Library Of Medicine
Study compared outcomes of transjugular intrahepatic portosystemic shunt (TIPS) to those of medical/endoscopic therapy for acute variceal bleeding in cirrhotic patients. TIPS did not significantly decrease the incidence of rebleeding.
Source: National Library Of Medicine
No standardized protocol for bowel preparation for capsule endoscopy has been evaluated. Bowel preparation with simethicone resulted in significantly better visibility because of fewer intraluminal bubbles
Source: National Library Of Medicine
Capsule endoscopy is a new diagnostic method allowing painless visualization of the entire small bowel. There is as yet no standardized protocol for bowel preparation before the examination.
Source: National Library Of Medicine
There were significantly more good quality endomicroscopic images in the propofol group than in the M/F group. The diagnostic accuracy for upper gastrointestinal mucosal lesions favors the P group. Adverse events and patient assessment were not significantly different for M/f vs propofols.
Source: National Library Of Medicine
Transnasal endoscopy (TNE) has some disadvantages, such as complicated preprocessing and occasional repulsion reactions during catheterization. In an attempt to simplify the preprocessing method, the efficacy of a catheter-free method was assessed
Source: National Library Of Medicine
Irritable bowel syndrome (IBS) is one of the most common functional bowel disorders. Community prevalence appears to vary widely between different countries. We did a systematic review and meta-analysis of data from all population-based studies.
Source: The Lancet
Transnasal endoscopy (TNE) has some disadvantages, such as complicated preprocessing and occasional repulsion reactions during catheterization. In an attempt to simplify the preprocessing method, the efficacy of a catheter-free method was assessed
Source: National Library Of Medicine
Small-bowel tumors frequently occur in familial adenomatous polyposis syndromes. These tumors are difficult to detect with conventional techniques.
Source: National Library Of Medicine
Pneumatic dilation of upper GI CD-associated strictures has a high rate of short-term technical and clinical success, with moderate long-term efficacy and acceptable complication rates
Source: National Library Of Medicine
Pharyngeal anesthesia is widely used as an adjunct to sedation during an upper endoscopy. This study evaluated the effectiveness of pharyngeal anesthesia in improving patient tolerance and ease of endoscope used. From a pool of 53 studies, 5 RCTs evaluated a total of 491 patients and provided interpretable data.
Source: National Library Of Medicine
SEDASYS System could provide endoscopist/nurse teams a safe and effective on-label means to administer propofol to effect minimal to moderate sedation during routine colonoscopy or EGD.
Source: National Library Of Medicine
The study compared the PGA shielding method with polyglycolic acid (PGA) sheets and fibrin glue for the prevention of adverse events after ESD. Post-ESD bleeding occurred in three patients (4.5%) in the PGA group and in four patients (5.7%) in a control group.
Source: National Library Of Medicine
After intravenous administration of indocyanine green (ICG), infrared endoscopy is used to examine vascular lesions such as esophageal varices. No previous study has compared the sensitivity of infrared fluorescence endoscope (IRFE) with that of IRE.
Source: National Library Of Medicine
A number of studies were able to show a reduction of hypoxemia episodes during procedural sedation through the use of capnography (CA) The study compared standard monitoring (SM) versus SM with additional CA surveillance.
Source: National Library Of Medicine
Narrow band imaging (NBI) system is used to capture clear images of microvessels on mucosal surfaces. This study measured the correlation between the magnified images obtained with the NBI system and the histological findings, especially with regard to the vascular pattern.
Source: National Library Of Medicine
Recommendations from the American Society of Anesthesiologists suggest that monitoring for apnea using the detection of exhaled carbon dioxide is a useful adjunct to the assessment of the ventilatory status of patients undergoing sedation and analgesia.
Source: National Library Of Medicine
The 5C scale, which assesses 5 psychological antecedents of vaccination, could be effective in exploring COVID-19 VH. Arab validated version of the 5C scale has a good discriminatory power to predict COVID-19 vaccines antecedent. Findings were published in the Journal of the American Academy of Public Health. The study aimed to determine a statistically valid cutoff point for the sub-scales.
Source: National Library Of Medicine
The first-generation COVID-19 vaccines are being trialed after initial evidence showed 70-95% efficacy and minimal risks. CDC study: Those with less education were more likely to be unwilling to be vaccinated. Overall predicted uptake is 68.81% by the end of Phase 2 (August 2021), which is well below the 75-90% needed for herd immunity. Effectiveness and safety had the largest effects.
Source: National Library Of Medicine
The study assessed psychosocial predictors of U.S. adults' willingness to get a future COVID-19 vaccine. Significant predictors were education, having insurance, a positive attitude toward the vaccine, as well as high perceived susceptibility to the vaccine. The study was published in the Journal of the American Public Health Association.
Source: National Library Of Medicine
The effectiveness of the COVID-19 vaccination program depends on mass participation. COVID-19 vaccine hesitancy had reduced from% the previous year to additional vaccine-hesitant adults. The study highlights the need for future health campaigns to engage with the public on terrain that is most salient.
Source: National Library Of Medicine
The aim of the study was to determine if there is sufficient literature to require clinicians to disclose the specific risk that COVID-19 vaccines could worsen disease upon exposure to challenge or circulating virus.Study looked at evidence that vaccines could worsen disease upon exposure to challenge or circulating viruses. Findings could have implications for future clinical trials. Vaccines for SARS, MERS, and RSV have never been approved by the.
Source: National Library Of Medicine