Urgent endoscopic retrograde cholangiopancreatography with sphincterotomy versus conservative treatment in predicted severe acute gallstone pancreatitis (APEC): a multicentre randomised controlled trial
Randomised trial compared urgent ERCP with sphincterotomy versus conservative treatment. The primary endpoint was a composite of mortality or major complications within 6 months of randomisation. No relevant differences in the individual components of the primary endpoint were recorded between groups, apart from the occurrence of cholangitis. Findings support a conservative strategy in patients with predicted severe acute gallstone pancreatitis with an E RCP indicated only in patients who have c
