Mental health before and during the COVID-19 pandemic: a longitudinal probability sample survey of the UK population

The potential impact of the COVID-19 pandemic on population mental health is of increasing global concern. Mental health was assessed using the 12-ite...

Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study

Concerns regarding potential neurological complications of COVID-19 are being increasingly reported. This is the first nationwide, cross-specialty sur...

Cannabidiol for the treatment of cannabis use disorder: a phase 2a, double-blind, placebo-controlled, randomised, adaptive Bayesian trial

A substantial and unmet clinical need exists for pharmacological treatment of cannabis use disorders. Cannabidiol could offer a novel treatment, but i...

Effectiveness of digital psychological interventions for mental health problems in low-income and middle-income countries: a systematic review and meta-analysis

The effectiveness of digital psychological interventions in low-income and middle-income countries remains unclear. We searched databases for articles...

Associations between statin use and suicidality, depression, anxiety, and seizures: a Swedish total-population cohort study

Statins have shown both protective and adverse associations with neuropsychiatric outcomes. Suicide outcomes were found in 6372 individuals, depressiv...

Brain-based mediation of non-conscious reduction of phobic avoidance in young women during functional MRI: a randomised controlled experiment

Exposure therapy is the treatment of choice for anxiety disorders but requires people to confront feared situations. VBE reduced fear non-consciously...

Environmental risk factors, protective factors, and peripheral biomarkers for ADHD: an umbrella review

Many potential environmental risk factors, environmental protective factors, and peripheral biomarkers for ADHD have been investigated. The consistenc...

Amisulpride, aripiprazole, and olanzapine in patients with schizophrenia-spectrum disorders (BeSt InTro): a pragmatic, rater-blind, semi-randomised trial

Amisulpride was more efficacious than aripiprazole or olanzapine for reducing the PANSS total scores in adults with schizophrenia-spectrum disorders....