Efficacy of Ramucirumab Versus Sorafenib as Subsequent Treatment for Hepatocellular Carcinoma
The study examined the therapeutic efficacy of ramucirumab compared with that of sorafenib as subsequent systemic therapy for patients with HCC. The P...
The effects of acute aerobic exercise on the acquisition and retention of laparoscopic skills
Study was to determine whether an episode of aerobic exercise improves laparoscopic skills. Participants ran on a treadmill for 20 min at 60% of their...
Pancreatic enzyme supplementation improves the incretin hormone response and attenuates postprandial glycemia in adolescents with cystic fibrosis: a randomized crossover trial
Pancreatic enzyme replacement therapy (PERT) reduced postprandial hyperglycemia and slowed gastric emptying in CF subjects. It also normalized GLP-1 a...
Early post-operative endoscopic recurrence in Crohn's disease patients: data from an Italian Group for the study of inflammatory bowel disease (IG-IBD) study on a large prospective multicenter cohort
The incidence of endoscopic recurrence in Crohn's disease following curative resection is up to 75% at 1 year. The study suggests post-surgical endosc...
Training and transfer of colonoscopy skills: a multinational, randomized, blinded, controlled trial of simulator versus bedside training
Simulator training significantly improved performance on simulated cases compared with patient-based training. Novices in the simulator group demonstr...
Efficacy and safety of certolizumab pegol in an unselected crohn's disease population: 26-week data of the FACTS II survey
This prospective phase IV study aimed to evaluate the efficacy and safety. Response and remission rates were 70% and 40% (week 6) and 67% and 36%, res...
The ACCURE-trial: the effect of appendectomy on the clinical course of ulcerative colitis, a randomised international multicenter trial (NTR2883) and the ACCURE-UK trial: a randomised external pilot trial (ISRCTN56523019)
Appendectomy might alter the clinical course of established UC. The objective of this body of research is to evaluate the short-term and medium-term e...
Randomized phase III trial in elderly patients comparing LV5FU2 with or without irinotecan for first-line treatment of metastatic colorectal cancer (FFCD 2001-02)
Four arms were randomly assigned to receive 5-FU (5-fluorouracil)-based CT. No significant difference was observed for the median PFS. Adding irinotec...
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