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The effectiveness of Lactobacillus reuteri DSM 17938 as an adjunct to macrogol in the treatment of functional constipation in children. A randomized, double-blind, placebo-controlled, multicentre trial

Constipation is one of the most common problems among children, with a prevalence ranging from 7 to 30%. It is treated with defecation training and la...

Self-sizing radiofrequency ablation balloon for eradication of Barrett's esophagus: results of an international multicenter randomized trial comparing 3 different treatment regimens

The 360 Express has replaced the traditional system for circumferential radiofrequency ablation (RFA) of Barrett's esophagus (BE) The aim was to compa...

MicroRNA-21 as a diagnostic marker for hepatocellular carcinoma: A systematic review and meta-analysis

MicroRNA-21 is one of the oncogenic miRNAs which may be a potential diagnostic biomarker for hepatocellular carcinoma (HCC) A total of 515 HCC patient...

Optimal bowel cleansing for colonoscopy: split the dose! A series of meta-analyses of controlled studies

Authors: Colonoscopy is considered the criterion standard for detecting colorectal cancer. They aim to assess the efficacy of split-dose versus non-sp...

Early use of double-guidewire technique to facilitate selective bile duct cannulation: the multicenter randomized controlled EDUCATION trial

There are no guidelines for the timing of conversion to a double-guidewire technique to facilitate selective bile duct cannulation and reduce post-end...

Therapeutic success with bismuth-containing sequential and quadruple regimens in Helicobacter pylori eradication

The success rate of Helicobacter pylori eradication with classical triple therapy is gradually declining. In this study, OTMB and OA+OCMB were signifi...

Endoscopic sphincterotomy for common bile duct stones in younger patients

The median observation time after endoscopic sphincterotomy was 27.1 months. Cholecystectomy was not needed in 27 patients, of whom 23 had gallbladder...

Efficacy of Ramucirumab Versus Sorafenib as Subsequent Treatment for Hepatocellular Carcinoma

The study examined the therapeutic efficacy of ramucirumab compared with that of sorafenib as subsequent systemic therapy for patients with HCC. The P...

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