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Geriatric factors analyses from FFCD 2001-02 phase III study of first-line chemotherapy for elderly metastatic colorectal cancer patients

Elderly patients (75+) with previously untreated mCRC were randomly assigned to receive infusional 5-fluorouracil-based chemotherapy. Normal IADL was...

An open-label prospective randomized multicenter study of intensive versus weekly granulocyte and monocyte apheresis in active crohn's disease

GMA has shown efficacy in patients with active Crohn's disease (CD) However, with routine weekly therapy, it may take several weeks to achieve remissi...

A randomized clinical trial of mesalazine suppository: the usefulness and problems of central review of evaluations of colonic mucosal findings

A double-blind, placebo-controlled, parallel-group trial was performed for 4weeks, which involved continuous administration of a 1-g mesalazine suppos...

Single-stage endoscopic treatment for mild to moderate acute cholangitis associated with choledocholithiasis: a multicenter, non-randomized, open-label and exploratory clinical trial

Two-stage treatment involving stone removal after drainage is recommended for mild to moderate acute cholangitis associated with choledocholithiasis

Evaluation of formal feedback on endoscopic competence among trainees: the EFFECT trial

The study aimed to characterize the impact of feedback on colonoscopy performance among gastroenterology (GI) trainees. After feedback, caecal intubat...

Algorithm-based management of patients with gastrointestinal symptoms in patients after pelvic radiation treatment (ORBIT): a randomised controlled trial

Chronic gastrointestinal symptoms after pelvic radiotherapy are common and affect patients' quality of life. Nurse-led algorithm-based treatment was f...

A prospective, randomized assessment of a spatial orientation device in natural orifice transluminal endoscopic surgery

The Queen's NOTES group has devised a novel method of orientation by using a magnetic device that passes within an endoscope channel allowing for 3-di...

An inter-observer agreement study of autofluorescence endoscopy in Barrett's esophagus among expert and non-expert endoscopists

Autofluorescence imaging (AFI) is associated with significant false-positive results during Barrett's surveillance. The aim of this study was to asses...

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