Clinical criteria for COVID-19-associated hyperinflammatory syndrome: a cohort study

A subset of patients with COVID-19 develops a hyperinflammatory syndrome that has similarities with other hyperinflammatory disorders. We developed a...

Safety and efficacy of abatacept in early diffuse cutaneous systemic sclerosis (ASSET): open-label extension of a phase 2, double-blind randomised trial

Abatacept was well tolerated by patients with early diffuse cutaneous systemic sclerosis. The primary endpoint was modified Rodnan Skin Score at 12 mo...

Serious postoperative complications and reoperation after carpal tunnel decompression surgery in England: a nationwide cohort analysis

Of the 855 832 initial surgeries, 620 procedures led to a serious complication within 30 days after surgery. The study is the largest national study o...

Sirolimus for treatment of patients with inclusion body myositis: a randomised, double-blind, placebo-controlled, proof-of-concept, phase 2b trial

Inclusion body myositis is most frequent in patients older than 50 years. In this pilot study, we aimed to test the efficacy of sirolimus in patients...

Temporal trends in severe COVID-19 outcomes in patients with rheumatic disease: a cohort study

We identified 8540 patients with rheumatic and musculoskeletal diseases who were diagnosed with COVID-19. Risk of hospitalisation was lower in the lat...