Identification and functional analysis of the SARS-COV-2 nucleocapsid protein
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was proved to be the main agent of COVID-19. SARS-COV- 2 N protein composed of 419 aa, is a 45.6 kDa positively charged unstable hydrophobic protein. It has 91 and 49% similarity to SARS and MERS and is predicted to be predominantly a nuclear protein. The 12 phosphorylated sites and 9 potential protein kinase sites may serve as promising targets for drug discovery and development.
