The ACE (Albumin, CRP and Endoscopy) Index in Acute Colitis: A Simple Clinical Index on Admission that Predicts Outcome in Patients With Acute Ulcerative Colitis
Intravenous (IV) steroids remain the first-line treatment for patients with acute ulcerative colitis. 30% of patients do not respond to steroids, requiring second-line therapy and/or surgery. Nonresponse was defined as a requirement for second-line therapy or surgery. 78.1% (25 of 32) of patients with concurrent CRP, albumin, and increased endoscopic severity did not respond to IV steroids. This combination of parameters identifies on admission a high-risk population.
