Circulating Levels of Interleukin-6 and Interleukin-10, But Not Tumor Necrosis Factor-Alpha, as Potential Biomarkers of Severity and Mortality for COVID-19: Systematic Review with Meta-analysis
Cytokine storm is an uncontrolled overproduction of inflammatory cytokines. It is a major pathological feature of acute respiratory distress syndromes being severe manifestations of COVID-19. A literature search in electronic databases consisting of PubMed, Scopus, and Cochrane Library and in a hand searching of reference lists. IL-6 and IL-10 might have great potential as biomarkers for the disease severity and mortality in COVID-19 patients.
