Population-based meta-analysis of chloroquine: informing chloroquine pharmacokinetics in COVID-19 patients
Chloroquine has been repurposed to treat coronavirus disease 2019 (COVID-19). To study its exposure-efficacy relationship and provide a basis for a possible dosing regimen optimization. Chloroquine has been repurposed to treat coronavirus disease 2019 (COVID-19). The derived population PK model should allow for the assessment of pharmacokinetics-pharmacodynamics (PK-PD) relationships for CQ when given alone or in combination with other agents to treat COVID-19.
