Randomized phase III trial in elderly patients comparing LV5FU2 with or without irinotecan for first-line treatment of metastatic colorectal cancer (FFCD 2001-02)
Metastatic colorectal cancer (mCRC) frequently occurs in elderly patients. The benefit of first-line CT intensification remains an issue. Four arms were randomly assigned to receive 5-FU (5-fluorouracil)-based CT.
