Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2

SARS-CoV-2 has caused a worldwide pandemic of coronavirus disease 2019 or COVID-19. Coronaviruses generate subgenomic RNAs through a process involving...

Persistent viral RNA shedding after COVID-19 symptom resolution in older convalescent plasma donors

SARS-CoV-2 is responsible for a worldwide pandemic. Less is known about how long viral shedding occurs once viral symptoms have resolved. We found evi...

A rapid, cost-effective tailed amplicon method for sequencing SARS-CoV-2

The global COVID-19 pandemic has led to an urgent need for scalable methods for clinical diagnostics and viral tracking. Given the small genome size,...

SARS-CoV-2 early infection signature identified potential key infection mechanisms and drug targets

2.3 million people have died worldwide as a result of SARS-CoV-2 infection. The disease mechanism is mostly unknown, and effective treatment options a...

Assessing critical gaps in COVID-19 testing capacity: the case of delayed results in Ecuador

WHO's preparedness index omits estimations of actual testing capabilities. Ecuador has one of the highest excess death rates globally. Ecuador had a c...

False-negative results of initial RT-PCR assays for COVID-19: A systematic review

False-negative cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have important implications for isolation and risk of transmissio...

Providing Oncology Pharmacy Services During the Coronavirus Pandemic: French Society for Oncology Pharmacy (Société Francaise de Pharmacie Oncologique [SFPO]) Guidelines

Patients with cancer are at higher risk for contracting the COVID-19 infection and are more likely to have higher morbidity and mortality. These guide...

Rapid and Extraction-Free Detection of SARS-CoV-2 from Saliva by Colorimetric Reverse-Transcription Loop-Mediated Isothermal Amplification

Rapid, reliable, and widespread testing is required to curtail the ongoing COVID-19 pandemic. We developed a rapid colorimetric assay using reverse-tr...

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