Systematic review: the quality of the scientific evidence and conflicts of interest in international inflammatory bowel disease practice guidelines

The study examined inflammatory bowel disease guidelines for quality of evidence, methods of grading evidence, and conflicts of interest. Nearly half...

Treatments for Crohn's Disease-Associated Bowel Damage: A Systematic Review

Most patients with Crohn's disease (CD) develop structuring or penetrating complications. Mechanisms of intestinal damage in patients with CD include...

The use of probiotics in pediatric gastroenterology: a review of the literature and recommendations by Latin-American experts

Probiotics can help treat acute infectious diarrhea, colic, necrotizing enterocolitis (NEC), inflammatory bowel disease, constipation, and allergy. La...

Systematic Review and External Validation of Prediction Models Based on Symptoms and Biomarkers for Identifying Endoscopic Activity in Crohn's Disease

Endoscopic healing, an important target of treatment for Crohn's disease (CD), requires ileocolonoscopy, which is costly and burdensome. We found only...

Adalimumab Monotherapy and a Combination with Azathioprine for Crohn's Disease: A Prospective, Randomized Trial

The study evaluated the efficacy of adalimumab with and without azathioprine in patients with active Crohn's disease. The rate of endoscopic improveme...

Best practices on immunomodulators and biologic agents for ulcerative colitis and Crohn's disease in Asia

The Asia-Pacific Working Group on Inflammatory Bowel Disease was established in Cebu, Philippines. It aims to improve inflammatory bowel disease care...

Prevalence, incidence, and outcome of non-alcoholic fatty liver disease in Asia, 1999-2019: a systematic review and meta-analysis

Non-alcoholic fatty liver disease is the most prevalent chronic liver disease worldwide. NAFLD prevalence in Asia is increasing and is associated with...