Systematic review: the quality of the scientific evidence and conflicts of interest in international inflammatory bowel disease practice guidelines
The study examined inflammatory bowel disease guidelines for quality of evidence, methods of grading evidence, and conflicts of interest. Nearly half...
Treatments for Crohn's Disease-Associated Bowel Damage: A Systematic Review
Most patients with Crohn's disease (CD) develop structuring or penetrating complications. Mechanisms of intestinal damage in patients with CD include...
The use of probiotics in pediatric gastroenterology: a review of the literature and recommendations by Latin-American experts
Probiotics can help treat acute infectious diarrhea, colic, necrotizing enterocolitis (NEC), inflammatory bowel disease, constipation, and allergy. La...
Early Use of Corticosteroid May Prolong SARS-CoV-2 Shedding in Non-Intensive Care Unit Patients with COVID-19 Pneumonia: A Multicenter, Single-Blind, Randomized Control Trial
There is still no clinical evidence available to support or to oppose corticosteroid treatment for coronavirus disease 2019 (COVID-19) pneumonia. This...
Systematic Review and External Validation of Prediction Models Based on Symptoms and Biomarkers for Identifying Endoscopic Activity in Crohn's Disease
Endoscopic healing, an important target of treatment for Crohn's disease (CD), requires ileocolonoscopy, which is costly and burdensome. We found only...
Adalimumab Monotherapy and a Combination with Azathioprine for Crohn's Disease: A Prospective, Randomized Trial
The study evaluated the efficacy of adalimumab with and without azathioprine in patients with active Crohn's disease. The rate of endoscopic improveme...
Best practices on immunomodulators and biologic agents for ulcerative colitis and Crohn's disease in Asia
The Asia-Pacific Working Group on Inflammatory Bowel Disease was established in Cebu, Philippines. It aims to improve inflammatory bowel disease care...
Prevalence, incidence, and outcome of non-alcoholic fatty liver disease in Asia, 1999-2019: a systematic review and meta-analysis
Non-alcoholic fatty liver disease is the most prevalent chronic liver disease worldwide. NAFLD prevalence in Asia is increasing and is associated with...