Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target
STRIDE program examined potential treatment targets for inflammatory bowel disease. The group agreed upon 12 recommendations for ulcerative colitis (U...
Respiratory Tract Manifestations of Inflammatory Bowel Disease
Inflammatory bowel disease can manifest in many extraintestinal organ systems. Most frequently involved extraintestinal locations include mucocutaneou...
90-Day Specific Readmission for Clostridium difficile Infection After Hospitalization With an Inflammatory Bowel Disease Flare: Outcomes and Risk Factors
Patients with inflammatory bowel disease have an increased risk for Clostridium difficile infection. We aimed to investigate disease-specific readmiss...
Preadmission Cannabis Use Is Positively Correlated With Inpatient Opioid Dose Exposure in Hospitalized Patients With Inflammatory Bowel Diseases
Opioid use is associated with excess mortality in patients with inflammatory bowel disease (IBD) It is unknown if preadmission use of cannabis increas...
Gluten Degradation, Pharmacokinetics, Safety, and Tolerability of TAK-062, an Engineered Enzyme to Treat Celiac Disease
Celiac disease (CeD) is an immune-mediated disorder triggered by the ingestion of gluten. TAK-062 is a novel, computationally designed endopeptidase u...
The receptor activator of nuclear factor κΒ ligand receptor leucine-rich repeat-containing G-protein-coupled receptor 4 contributes to parathyroid hormone-induced vascular calcification
In chronic kidney disease, serum phosphorus (P) elevations stimulate parathyroid hormone (PTH) production. PTH is the main regulator of the receptor a...
Effects of empagliflozin on first and recurrent clinical events in patients with type 2 diabetes and atherosclerotic cardiovascular disease: a secondary analysis of the EMPA-REG OUTCOME trial
EMPA-REG OUTCOME trial was a randomized, double-blind, non-inferiority trial of patients with type 2 diabetes and atherosclerotic cardiovascular disea...
Laparoscopic ileocaecal resection versus infliximab for terminal ileitis in Crohn's disease: retrospective long-term follow-up of the LIR!C trial
LIR! C trial showed laparoscopic ileocaecal resection is a cost-effective treatment for Crohn's disease. It has similar quality-of-life outcomes to tr...
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