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Systematic review with meta-analysis: rifaximin is effective and safe for the treatment of small intestine bacterial overgrowth

Rifaximin has gained popularity for this indication despite its use is not evidence-based. It seems to be effective and safe for the treatment of SIBO...

Endoscopic or surgical step-up approach for infected necrotising pancreatitis: a multicentre randomised trial

The rate of pancreatic fistulas and length of hospital stay were lower in the endoscope group than in the surgery group. The outcome of this trial wil...

Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial

Fecal microbiota transplantation is a novel form of therapeutic microbial manipulation but its efficacy in ulcerative colitis is uncertain. Intensive-...

Urgent endoscopic retrograde cholangiopancreatography with sphincterotomy versus conservative treatment in predicted severe acute gallstone pancreatitis (APEC): a multicentre randomised controlled trial

Randomised trial compared urgent endoscopic retrograde cholangiopancreatography with biliary sphincterotomy with conservative treatment in gallstone p...

Efficacy and Safety of Early vs Elective Colonoscopy for Acute Lower Gastrointestinal Bleeding

170 patients with acute lower gastrointestinal bleeding were randomly assigned (1:1) to groups that underwent early colonoscopy. Rebleeding within 30...

AGA Institute Rapid Review of the Gastrointestinal and Liver Manifestations of COVID-19, Meta-Analysis of International Data, and Recommendations for the Consultative Management of Patients with COVID-19

Multiple gastrointestinal (GI) symptoms, including diarrhea, nausea/vomiting, and abdominal pain, have been reported in patients with coronavirus dise...

A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis

Fibrates are agonists of peroxisome proliferator-activated receptors. They have shown potential benefit in patients with primary biliary cholangitis.

Prevalence, incidence, and outcome of non-alcoholic fatty liver disease in Asia, 1999-2019: a systematic review and meta-analysis

Non-alcoholic fatty liver disease is the most prevalent chronic liver disease worldwide. NAFLD prevalence in Asia is increasing and is associated with...

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