Phenotype and Natural History of Inflammatory Bowel Disease in Patients With Concomitant Eosinophilic Esophagitis

Eosinophilic esophagitis (EoE) is more common in patients with inflammatory bowel diseases. Cases consisted of patients with IBD and EoE, with both di...

TRIM21 Is Decreased in Colitis-associated Cancer and Negatively Regulates Epithelial Carcinogenesis

Tripartite motif-containing (TRIM)21 is reported to be associated with the regulation of immune response in the gut mucosa. We analyzed TRIM21 expres...

The ACE (Albumin, CRP and Endoscopy) Index in Acute Colitis: A Simple Clinical Index on Admission that Predicts Outcome in Patients With Acute Ulcerative Colitis

Intravenous (IV) steroids remain the first-line treatment for patients with acute ulcerative colitis. 30% of patients do not respond to steroids, requ...

Risk Stratification Score Improves Sensitivity for Advanced Colorectal Neoplasia in Colorectal Cancer Screening: The Oshima Study Workgroup

Noninvasive colorectal cancer (CRC) screening methods with higher sensitivity than the fecal immunochemical test (FIT) alone are warranted. Analysis o...

Smoking, Genetic Predisposition, and Colorectal Cancer Risk

Smoking and genetic predisposition are established risk factors for colorectal cancer. A PRS above the 90th percentile was significantly associated wi...

Lymph Node Tumor Burden Correlates With Tumor Budding and Poorly Differentiated Clusters: A New Prognostic Factor in Colorectal Carcinoma?

Molecular lymph node (LN) staging in early colorectal cancer has demonstrated to be more precise than conventional histopathology pN staging. 5,931 LN...

Gallstone Cause

What causes gallstones? Gallstones are thought to develop because of an imbalance in the chemical make-up of bile inside the gallbladder. In most case...

Hernia

A hernia is the abnormal exit of tissue or an organ, such as the bowel, through the wall of the cavity in which it normally resides. Hernias come in a...