Molecular and serological characterization of SARS-CoV-2 infection among COVID-19 patients
More than 80% of COVID-19 patients exhibit mild or moderate symptoms. Respiratory SARS-CoV-2 RNA was detectable in 58.0% (58/100) patients upon admiss...
Evaluation of potential anti-RNA-dependent RNA polymerase (RdRP) drugs against the newly emerged model of COVID-19 RdRP using computational methods
Despite all the efforts to treat COVID-19, no particular cure has been found for this virus. As a vital component in the life cycle of coronaviruses,...
A single center cohort of 40 severe COVID-19 patients who were treated with convalescent plasma
Convalescent plasma (CP) was previously used successfully to treat SARS-CoV-1 and MERS infections. Nine out of 10 patients who have received CP outsid...
Quantifying the potential value of antigen-detection rapid diagnostic tests for COVID-19: a modelling analysis
In a hospital setting, an Ag-RDT-led strategy would avert more deaths than a NAT-based strategy, and at a lower cost per death averted. We evaluated t...
Detection of SARS-CoV-2 in fecal samples with different pretreatment methods and PCR kits
Fecal sample testing with real-time RT-PCR is highly recommended as a routine test for SARS-CoV-2 infection. 39.29% detection rate in the fecal sample...
Improving Detection Efficiency of SARS-CoV-2 Nucleic Acid Testing
SARS-CoV-2 nucleic acid testing (NAT) has been routinely used for diagnosis during this pandemic. There have been concerns about its high false-negati...
Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2
SARS-CoV-2 has caused a worldwide pandemic of coronavirus disease 2019 or COVID-19. Coronaviruses generate subgenomic RNAs through a process involving...
Persistent viral RNA shedding after COVID-19 symptom resolution in older convalescent plasma donors
SARS-CoV-2 is responsible for a worldwide pandemic. Less is known about how long viral shedding occurs once viral symptoms have resolved. We found evi...
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