A rapid, cost-effective tailed amplicon method for sequencing SARS-CoV-2

The global COVID-19 pandemic has led to an urgent need for scalable methods for clinical diagnostics and viral tracking. Given the small genome size,...

SARS-CoV-2 early infection signature identified potential key infection mechanisms and drug targets

2.3 million people have died worldwide as a result of SARS-CoV-2 infection. The disease mechanism is mostly unknown, and effective treatment options a...

Assessing critical gaps in COVID-19 testing capacity: the case of delayed results in Ecuador

WHO's preparedness index omits estimations of actual testing capabilities. Ecuador has one of the highest excess death rates globally. Ecuador had a c...

False-negative results of initial RT-PCR assays for COVID-19: A systematic review

False-negative cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have important implications for isolation and risk of transmissio...

Rapid and Extraction-Free Detection of SARS-CoV-2 from Saliva by Colorimetric Reverse-Transcription Loop-Mediated Isothermal Amplification

Rapid, reliable, and widespread testing is required to curtail the ongoing COVID-19 pandemic. We developed a rapid colorimetric assay using reverse-tr...

Serial interval and incubation period of COVID-19: a systematic review and meta-analysis

Combining findings of existing studies that estimate the average serial interval and incubation period of COVID-19 significantly improves the quality...

Infection and disease spectrum in individuals with household exposure to SARS-CoV-2: A family cluster cohort study

SARS-CoV-2 has a high frequency of transmission among household contacts. Children and adults are less likely to develop the symptomatic disease.