Use of the variplex™ SARS-CoV-2 RT-LAMP as a rapid molecular assay to complement RT-PCR for COVID-19 diagnosis

The assay may be useful for rapid diagnosis of the severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) because of the easy performance and the option to bypass RNA extraction. Using isolated RNA variplex™ RT-LAMP showed a sensitivity of 75% compared to LightMix E gene RT-PCR but contrary to the latter it produced no false-positive results.

Conjunctivitis as sole symptom of COVID-19: A case report and review of literature

Conjunctivitis is presented as the sole symptom of a new coronavirus disease 2019 (COVID-19) in an emergency health care worker. The patient's first application was to the ophthalmology clinic due to redness, stinging, tearing, and photophobia for one day in the right eye

High-Throughput Transcription-mediated amplification on the Hologic Panther is a highly sensitive method of detection for SARS-CoV-2

The Optima SARS-CoV-2 Assay has only recently received Emergency Use Authorization (EUA) by the Food and Drug Administration (FDA) TMA provides an effective, highly sensitive means of detection of SARS in nasopharyngeal specimens

Non-physician performance of lower and upper endoscopy: a systematic review and meta-analysis

The study objective was to characterize the non-physician performance of lower and upper endoscopic procedures. Bibliographical searches were conducted in Medline, EMBASE, and Cochrane Library databases. outcomes and rate ratios were determined.

Premedication with sublingual or oral alprazolam in adults undergoing diagnostic upper gastrointestinal endoscopy

Diagnostic esophagogastroduodenoscopy (EGD) is uncomfortable for most patients. We determined the efficacy of alprazolam, administered orally or sublingually, as premedication for sedation during EGD.

Determination of the optimal time for premedication with pronase, dimethylpolysiloxane, and sodium bicarbonate for upper gastrointestinal endoscopy

Premedication with pronase, dimethylpolysiloxane, and sodium bicarbonate improves visibility during upper gastrointestinal (UGI) endoscopy. The optimal time for this combination to take effect is unknown. We investigated the optimal time of pre-UGI premedication.

Determination of the optimal time for premedication with pronase, dimethylpolysiloxane, and sodium bicarbonate for upper gastrointestinal endoscopy

Premedication with pronase, dimethylpolysiloxane, and sodium bicarbonate improves visibility during upper gastrointestinal (UGI) endoscopy. The optimal time for this combination to take effect is unknown. We investigated the optimal time of pre-UGI premedication.

Efficacy and safety of over-the-scope clips for gastrointestinal bleeding: a systematic review and meta-analysis

The over-the-scope clip (OTSC) has been increasingly utilized for the management of gastrointestinal (GI) bleeding. This systematic review showed high rates of definitive hemostasis, technical success, and clinical success, along with low rebleeding rates when OTSCs were used for the treatment of GI bleeding.

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