Effects of sedation during upper gastrointestinal endoscopy on arterial oxygen saturation

The study was designed to see the effect of sedation on endoscopy-induced arterial oxygen desaturation. 90 consecutive patients scheduled for diagnostic upper gastrointestinal endoscopes were divided into two groups. Patients in the first group were sedated with midazolam 0.1 mg/kg, propofol 1mg/kg and fentanyl 1 microg/kg intravenously, while the second group received saline as a placebo.

Sedation-associated complications in endoscopy--prospective multicentre survey of 191142 patients

Propofol sedation bears the risk of complications such as respiratory as well as cardiopulmonary insufficiency including sedation-induced death. Conclusion: This large prospective survey shows that propofol. sedation in gastrointestinal endoscopy is a safe procedure with a low. the potential of risk in daily routine.

Unsedated transnasal versus conventional oral endoscopy in endoscopy naïve patients

Unsedated transnasal upper endoscopy (TNE) has been suggested as a more comfortable and safer method than unsedated transoral endoscopes (TOE) The current study aimed to assess the tolerability, safety, and efficacy of TNE in endoscopy naive patients.

Drinking before endoscopy: milk or water?

Drinking water up to 90 minutes prior to endoscopy is safe, but milk should be discouraged because of suboptimal mucosal views, authors say. The study found no difference between water and milk in residual gastric volume or pH

Capsule endoscopy or push enteroscopy for first-line exploration of obscure gastrointestinal bleeding?

The position of capsule endoscopy (CE) in the diagnostic algorithm of obscure gastrointestinal bleeding is unclear. We conducted a trial in which patients were randomized to undergo one or other exploration

Effectiveness of nurse delivered endoscopy: findings from randomised multi-institution nurse endoscopy trial (MINuET)

Nurses were more thorough than doctors in examining the stomach and oesophagus. Patients were more satisfied with nurses after one day of endoscopy than after one month

Integration of a Robotic Platform for Sacrocolpopexy in Transvaginal Natural Orifice Transluminal Endoscopic Surgery: A Novel Surgical Technique

Robotic-assisted transvaginal surgery is a feasible and alternative to laparoscopic surgery. We report on two patients with stage II apical pelvic organ prolapse who underwent the new technique.

Systematic Review of the Preclinical Technology Readiness of Orthopedic Gene Therapy and Outlook for Clinical Translation

Gene therapy has been proposed as a possible approach to improve or augment bone healing. Small animal models that support the use of gene therapy do not recapitulate key features of a critical or complex fracture environment. Larger animal models are therefore a key step on the path to clinical translation of the technology

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