SARS-CoV-2: From the pathogenesis to potential anti-viral treatments

In this week's edition of the Sunday supplement, the author takes a look at what is happening in this one of the most pivotal moments of the year for the human race.

Analytical and Clinical Analysis of Two Automated Anti-SARS-CoV-2 Immunoassays in Pre-Pandemic and Pandemic Patient Populations

In the absence of a safe, effective vaccine, the worldwide spread of COVID-19 (SARS-CoV-2) infection will continue. Laboratory tests with ideal precision, sensitivity, and specificity should be used to gauge the extent of virus exposure. We evaluated the analytical and clinical performance of the Abbott and the Roche SARS- covirus-2 immunoassays

Evidence and magnitude of the effects of meteorological changes on SARS-CoV-2 transmission

Fifty representative Northern Hemisphere countries meeting specific criteria had sufficient COVID-19 case and meteorological data for analysis. This model of the effect of decreasing temperatures can only be verified over time as the pandemic proceeds through colder months.

Analysis and validation of a highly sensitive one-step nested quantitative real-time polymerase chain reaction assay for specific detection of severe acute respiratory syndrome coronavirus 2

Reverse transcriptase real-time quantitative polymerase chain reaction (qRT-PCR) is widely used as the gold standard for clinical detection of SARS-CoV-2. In this study, we aimed to analyze OSN-qRT -PCR by comparing it with droplet digitalPCR and qRT- PCR.

Seroprevalence of SARS-CoV-2 infection among children in Children's Hospital Zagreb during the initial and second wave of COVID-19 pandemic in Croatia

Study aimed to investigate prevalence and titres of anti-SARS-CoV-2 antibodies in children treated at the Children's Hospital Zagreb. In first time point 2.9% of seropositive children were determined and in second time point 8.4%.

Specificity and positive predictive value of SARS-CoV-2 nucleic acid amplification testing in a low-prevalence setting

Cities around the U.S. have seen a rise in violence in recent years. Some communities have tried to put an end to the problem by going after the culprits. One town tried to go after the people who had just been in a violent attack.

Clarithromycin Versus Metronidazole as First-line Helicobacter pylori Eradication: A Multicenter, Prospective, Randomized Controlled Study in Japan

Helicobacter pylori eradication rates have recently fallen to 80% because of an increasing incidence of resistance in Japan. This study compared the eradication success of 2 first-line triple therapy regimens: rabeprazole, amoxicillin, and clarithromycin (RAC) versus rabepazole,AmX, and metronidazole ( RAM) The eradication rate of RAM therapy was significantly higher than that of RAC therapy.

Clarithromycin Versus Metronidazole as First-line Helicobacter pylori Eradication: A Multicenter, Prospective, Randomized Controlled Study in Japan

Helicobacter pylori eradication rates have recently fallen to 80% because of an increasing incidence of resistance in Japan. This study compared the eradication success of 2 first-line triple therapy regimens: rabeprazole, amoxicillin, and clarithromycin (RAC) versus rabepazole,AmX, and metronidazole ( RAM) The eradication rate of RAM therapy was significantly higher than that of RAC therapy.

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