Objective benefit of a 1-day training course in endoscopic hemostasis using the "compactEASIE" endoscopy simulator

The Erlangen Active Simulator for Interventional Endoscopy (EASIE) was introduced in 1997. Objective evidence of the benefits of training with this model has not previously been published

Objective benefit of a 1-day training course in endoscopic hemostasis using the "compactEASIE" endoscopy simulator

The Erlangen Active Simulator for Interventional Endoscopy (EASIE) was introduced in 1997. Objective evidence of the benefits of training with this model has not previously been published

Furazolidone-containing triple and quadruple eradication therapy for initial treatment for Helicobacter pylori infection: A multicenter randomized controlled trial in China

A national, multicenter, open-label, randomized controlled trial was performed at 16 sites across 13 provinces in China. Treatment success was assessed by the 13 C urea breath test at least 4 weeks after treatment completion.

Therapeutic success with bismuth-containing sequential and quadruple regimens in Helicobacter pylori eradication

OTMB and OA+OCMB were significantly superior to the triple therapy and succeeded to reach the eradication rate proposed by the Maastricht consensus (over 80%) These two bismuth-containing regimens could be considered for first-line therapy in the regions with high clarithromycin resistance, we say

G-EYE colonoscopy is superior to standard colonoscopy for increasing adenoma detection rate: an international randomized controlled trial (with videos)

The G-EYE device includes a reusable balloon integrated at the distal tip of a standard colonoscope. Balloon-assisted colonoscopy provided a 48.0% ADR compared with 37.5% in the standard colonoscopic group. It also increased the detection of advanced, flat, and sessile serrated adenomas/polyps by 28% compared with the standard procedure. The study was a randomized, controlled, international, multicenter study (11 centers)

Frequency of use and standards of care for the use of azathioprine and 6-mercaptopurine in the treatment of inflammatory bowel disease: a systematic review of the literature and a survey of Canadian gastroenterologists

Azathioprine and 6-mercaptopurine were used to treat an average of 7% of patients. Liver enzyme and pancreatic enzyme levels were monitored by 62% and 29% of respondents respectively. Severe leukopenia (less than 2.10 g/L) occurs in less than 2% of cases and is sometimes associated with serious outcomes, including death. The risk of non-Hodgkin's lymphoma is likely low.

Randomized Phase II Study of Consecutive-Day versus Alternate-Day Treatment with S-1 as Second-Line Chemotherapy in Advanced Pancreatic Cancer

Study evaluated alternate-day administration of S-1 as second-line chemotherapy for unresectable pancreatic cancer in a multicenter, randomized, phase II study. Median OS was 4.5 months for the daily group and 4.4 months in the alternate- day group. Grade 3 or higher adverse events occurred with significantly higher incidence in the Daily group.

D-dimer levels and COVID-19 severity: Systematic Review and Meta-Analysis

Coronavirus disease 2019 (COVID-19) is a fatal and pandemic disease discovered in December 2019 in Wuhan. High d-dimer levels could predict disease severity, lung complications, and thrombose findings. We evaluated severe patients with total D- dimer levels.