The Maxingshigan decoction for treating COVID-19: A protocol for systematic review and meta-analysis

Many commonly used drugs for the treatment of COVID-19 have not shown excellent clinical effects. This study only screens clinical randomized controlled trials on MXSG for COVID-19 to evaluate its efficacy and safety. Traditional Chinese medicine has a long clinical history of preventing and treating this respiratory infectious disease. This systematic review is to provide new evidence for the effectiveness and safety of Maxingshigan decoction in the treatment of COVID-19.

The chronic kidney disease and acute kidney injury involvement in COVID-19 pandemic: A systematic review and meta-analysis

There are controversies about whether preexisting chronic kidney disease (CKD) and acute kidney injury complications are involved in the COVID-19 pandemic. Studies reported the kidney outcomes in different severity of COVID-19 were included in this study. CRRT is applied frequently in severe COVID-19 patients than that in nonsevere COVID-19 patients. The risk of AKI is higher in the critical group than that in the severe group.

Prevalence and impact of the cardiac injury on COVID-19: A systematic review and meta-analysis

The exact prevalence and impact of cardiac injury in hospitalized patients with coronavirus disease 2019 are still controversial. We searched the Cochrane Library, PubMed, MedRxiv, and EMBASE databases from December 2019 to July 15, 2020. Cardiac injury is associated with an increased risk of all-cause mortality in patients with coronavirus disease 2019. This was the first meta-analysis exploring the prevalence and impact of cardiac injury on COVID-19.

Clinical symptoms, comorbidities and complications in severe and non-severe patients with COVID-19: A systematic review and meta-analysis without cases duplication

The pandemic of COVID-19 poses a challenge to global healthcare. The mortality rates of severe cases of COVID-19 range from 8.1% to 38%. Hypertension, diabetes, and cardiovascular diseases may be risk factors. Prevalence of acute respiratory distress syndrome, acute kidney injury, and shock is higher in severe cases.

The limited Sensitivity of Chest Computed Tomography Relative to Reverse Transcription Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus-2 Infection: A Systematic Review on COVID-19 Diagnostics

Several studies suggest the sensitivity of chest CT is far greater than that of reverse transcription-polymerase chain reaction (RT-PCR) This systematic review aims to stratify studies as high or low risk of bias to determine the true sensitivity of CT. For chest CT, the mean sensitivity reported by biased studies was 94%. Difference between the sensitivities of CT and RT-PCR for severe acute respiratory syndrome coronavirus-2 infection.

Prevalence and impact of cardiac injury on COVID-19: A systematic review and meta-analysis

The exact prevalence and impact of cardiac injury in hospitalized patients with coronavirus disease 2019 are still controversial. we aim to investigate the prevalence of cardiac injury and its impact on the outcomes in patients with COVID-19. Cardiac injury is associated with an increased risk of all-cause mortality. In severe cases, cardiac injury is also associated with a higher risk of death.

Remdesivir for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials

Remdesivir was among the first antiviral therapies to be tested in RCTs for COVID-19. At a follow-up of 28-29 days, the use of remdesivir was not associated with a significant decrease in time to clinical improvement. Moderate and very low certainty of evidence showed there was no significant difference in deaths and developing any adverse events. Remdesivir was associated with higher rates of hospital discharge, but not with a significant reduction in the meantime to clinical improvement or mor

Ozone therapy for patients with COVID-19 pneumonia: Preliminary report of a prospective case-control study

The study involved 18 patients with COVID-19 infection (laboratory-confirmed) severe pneumonia. Each treatment involved the administration of whole blood enriched with an oxygen-ozone mixture. Ozonated autohemotherapy was associated with a shorter time to clinical improvement.

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