Interlaboratory Agreement of Anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Serologic Assays in the Expedited College of American Pathologists Proficiency Testing Program

SARS-CoV-2 is a pandemic virus and the etiologic agent of coronavirus disease 2019 (COVID-19) Clinical testing for antibodies to the virus has rapidly become widespread. The College of American Pathologists developed a new proficiency testing survey for anti-SARS -CoV -2 antibody assays. Results were analyzed for agreement by immunoglobulin (Ig) isotype tested, assay manufacturer, and methodology.

SARS-CoV-2 Serological testing in frontline health workers in Zimbabwe

Our first aim was to determine both the infection status and seroprevalence of SARS-CoV-2 in health workers. Second aim to evaluate the occupational and demographic predictors of seropositivity. We invited 713 staff members at 24 out of 35 health facilities in the City of Bulawayo in Zimbabwe. Of the 635 people (aged 18-73) providing a blood sample 39.1% reported a history of past COVID-19 symptoms while 14.2% reported having current symptoms.

Comparative evaluation of six nucleic acid amplification kits for SARS-CoV-2 RNA detection

accurate virus detection plays a crucial role in the current public health crisis. Quantitative real-time reverse transcriptase-polymerase chain reaction (RT-qPCR) kits have been reliably used for detection of SARS-CoV-2 RNA since the beginning of the outbreak. This is the first comparative study to evaluate CPA and RT-q PCR kits' specificity and sensitivity for Sars-Cov-2 detection. It could serve as a reference for clinical laboratories, thus informing testing protocols.

Vertical transmission of Severe Acute Respiratory Syndrome Coronavirus 2: A scoping review

Evidence for vertical transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is not well established. Of 336 newborns screened for COVID-19, only 15 were positive for throat swab RT-PCR. Of those 15, only five neonates were delivered by cesarean section. There is not enough evidence on vertical virologic transmission of Covid-19 infection during the third trimester of pregnancy. Further research involving an adequate sample size of breast milk, placenta, amniotic fluid, and

Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection

Accurate rapid diagnostic tests for SARS-CoV-2 infection could contribute to clinical and public health strategies to manage the pandemic. Point-of-care antigen and molecular tests to detect current infection could increase access to testing and early confirmation of cases. We present sensitivity and specificity with 95% confidence intervals (CIs) for each test and pooled data using the bivariate model for antigen and Molecular-based tests. We tabulated results by test manufacturer and complianc

SARS-CoV-2 is associated with high viral loads in asymptomatic and recently symptomatic healthcare workers

Healthcare workers are at increased risk of SARS-CoV-2 infection from both patients and other HCW with coronavirus disease 2019 (COVID-19) First 7-9 days of symptoms are associated with enhanced infectivity.

Pediatric Urology and International Medical Volunteerism: Where Are We? Where Are We Going?

A questionnaire regarding IVM participation was distributed to Societies for Pediatric Urology members (SPU), pediatric urology fellows (PUFs), and pediatric urologic fellowship program directors (PDs) Results in 98 of 733 SPU members queried responded; 62/98 (63%) having volunteered.

Satisfaction with Alignment After Reduction of a Displaced Distal Radial Fracture

Surgeons are influenced by radiographic deformity but do not agree on adequate alignment after reduction. satisfaction with reduction was fair and there was no evidence of significant variation

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