Quality Improvement in Gastroenterology: A Systematic Review of Practical Interventions for Clinicians
A review of quality improvement literature in gastroenterology revealed common themes of successful programs. Education was frequently used but often insufficient. EMR may be underutilized in guiding decision making, and patient-reported outcomes were infrequently assessed.
Comparison of Underwater vs Conventional Endoscopic Mucosal Resection of Intermediate-Size Colorectal Polyps
Endoscopic mucosal resection with submucosal injection is an established method for removing colorectal polyps. The en bloc resection rate decreases when polyp size exceeds 10mm.
Proactive Monitoring of Adalimumab Trough Concentration Associated With Increased Clinical Remission in Children With Crohn's Disease Compared With Reactive Monitoring
Proactive monitoring of drug trough concentrations and antibodies against drugs might help determine whether patients
Systematic Review and External Validation of Prediction Models Based on Symptoms and Biomarkers for Identifying Endoscopic Activity in Crohn's Disease
Endoscopic healing, an important target of treatment for Crohn's disease (CD), requires ileocolonoscopy, which is costly and burdensome. We found only 2 of 7 models evaluated to have NPVs of 90% or more but only a small proportion of patients with the endoscopic activity of CD were correctly predicted.
Step-up empiric elimination diet for pediatric and adult eosinophilic esophagitis: The 2-4-6 study
Milk and wheat/gluten are the most common food triggers for eosinophilic esophagitis (EoE) Step-up diets with few food triggers can be effective in EoE remission, they say. Authors: A TFGED diet achieves remission in 43% of children and adults.
The impact of Helicobacter pylori infection, eradication therapy and probiotic supplementation on gut microenvironment homeostasis: An open-label, randomized clinical trial
Helicobacter pylori is associated with the remodeling of gastric microbiota. Abundances of most butyrate-producing bacteria significantly decreased, while several detrimental bacteria increased after eradication therapy
Efficacy of Endoscopic Resection and Selective Chemoradiotherapy for Stage I Esophageal Squamous Cell Carcinoma
Esophagectomy is the standard treatment for stage I esophageal squamous cell carcinoma. A combination of ER and selective CRT was confirmed to be a minimally invasive treatment option.
Adalimumab Monotherapy and a Combination with Azathioprine for Crohn's Disease: A Prospective, Randomized Trial
The study evaluated the efficacy of adalimumab with and without azathioprine in patients with active Crohn's disease. The rate of endoscopic improvement was significantly higher in the combination group than in the monotherapy group.