Venous thromboembolism in patients with COVID-19: Systematic review and meta-analysis

Venous thromboembolism (VTE) may complicate the course of Coronavirus Disease 2019 (COVID-19) Study looked for studies that evaluated the incidence of VTE, including pulmonary embolism and deep vein thrombosis. Corresponding values in general wards were respectively 9% and 7%.VTE represents a frequent complication in hospitalized COVID-19 patients and often occurs as PE.

Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults

Therapies to interrupt the progression of early coronavirus disease 2019 (Covid-19) remain elusive. Among them, convalescent plasma administered to hospitalized patients has been unsuccessful, perhaps because antibodies should be administered earlier in the course of illness. The severe respiratory disease developed in 13 of 80 patients who received convalescent plasma. The trial was stopped early at 76% of its projected sample size. No solicited adverse events were observed.

COVID-19 and Headache Medicine: A Narrative Review of Non-Steroidal Anti-Inflammatory Drug (NSAID) and Corticosteroid Use

The use of non-steroidal anti-inflammatory drugs and corticosteroids in patients during the COVID-19 pandemic has been controversial. Evidence for or against the use of these medications is sparse. Clinicians should talk to their patients about the potential risks and benefits of using these medications during the pandemic.

Why does COVID-19 kill more elderly men than women? Is there a role for testosterone?

There may be a gender predisposition to COVID-19, with men predisposed to being most severely affected, and older men accounting for most deaths. Review of the research literature on the potential link between testosterone and COVID-19 induced mortality in elderly men. SARS-CoV-2 binds to the angiotensin-converting enzyme 2, present in high levels in the testis. Elevated IL-6 linked to the development of acute respiratory distress syndrome.

Medications in COVID-19 patients : summarizing the current literature from an orthopaedic perspective

The review aims to provide a summary of the current literature regarding common medications. All clinical studies, reviews, consensus, and guidelines related to the above medications and COVID-19 were included. Paracetamol remains the first line of analgesia and antipyretic for COVID-19 patients. opioids have the potential for immunosuppression in addition to respiratory depression. Orthopedic surgeons following up on patients who are using steroids should continue to follow up for possible avas

The vitamin D for COVID-19 (VIVID) trial: A pragmatic cluster-randomized design

High-dose vitamin D3 supplementation will reduce the risk of hospitalization/death among those with COVID-19 infection. The study involved 1500 newly diagnosed individuals with COVID-19 infection. They were randomized to either vitamin D3 (loading dose, then 3200 IU/day) or placebo. The primary outcome was the occurrence of hospitalization and/or mortality.

Cancer patients and research during COVID-19 pandemic: A systematic review of current evidence

The novel coronavirus, also known as SARS-Cov-2 or COVID-19 has become a worldwide threat. Cancer research was directly affected by the emerging of this disease. According to some Chinese studies, cancer patients are more vulnerable to complications. This observation led many oncologists to change their daily practice in cancer care.

Vitamin D insufficiency as a potential culprit in critical COVID-19 patients

Vitamin D has been implicated in the coronavirus disease- 2019 outcome. We aim to systematically explore the association of vitamin D serum levels with COVID-19 severity and prognosis. Patients with poor prognosis had significantly lower serum levels of vitamin D compared with those with a good prognosis. Diagnosis of vitamin C deficiency could be a helpful adjunct to assessing patients' potential of developing severe COVID-19.

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