Pregnancy and Breastfeeding During COVID-19 Pandemic: A Systematic Review of Published Pregnancy Cases

Study reviews knowledge on the impact of COVID-19 on pregnancy. 2,059 published cases with pregnancy outcomes resulted in 42 abortions, 21 stillbirths, and 2,015 live births. Preterm birth occurred in 23% of cases. Around 6% of pregnant women required admission to an intensive care unit and 28 died. 10 neonatal deaths.

Medications in COVID-19 patients: summarizing the current literature from an orthopaedic perspective

The review aims to provide a summary of the current literature regarding common medications prescribed in orthopedic surgery. Paracetamol remains the first line of analgesia and antipyretic.

COvid-19 and high-dose VITamin D supplementation TRIAL in high-risk older patients (COVIT-TRIAL): study protocol for a randomized controlled trial

The COVIT-TRIAL study is an open-label, multicenter, randomized controlled superiority trial. The primary outcome measure is all-cause mortality within 14 days of inclusion.

False-negative results of initial RT-PCR assays for COVID-19: A systematic review

False-negative cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have important implications for isolation and risk of transmission. Up to 54% of COVID-19 patients may have an initial false-negative RT-PCR (very low certainty of the evidence) The collected evidence has several limitations, including the risk of bias issues, high heterogeneous results, and concerns about its applicability.

COVID 19 therapies and anti-cancer drugs: A systematic review of recent literature

Main drug interactions were found with tocilizumab, ruxolitinib, and colchicine. Future clinical trials are needed to better understand interactions between different drugs in the context of the COVID-19 pandemic.

Epidemiology of COVID-19 infection in young children under five years: A systematic review and meta-analysis

COVID-19 infection in young children under five years is the most at-risk age group for respiratory infections. We searched several electronic databases for studies reporting laboratory-confirmed COVID- 19 infections in children under 5 years.

COVID-19 and Smoking: A Systematic Review and Meta-Analysis of the Evidence

Tobacco use in patients with Covid-19 is associated with a negative disease course and adverse outcomes. Being a smoker or former smoker was shown to be a risk factor for the worse progression of the disease.

Severe COVID-19 Infection and Pediatric Comorbidities: A Systematic Review and Meta-Analysis

There is limited information on the severity of COVID-19 infection in children with comorbidities. Children with underlying conditions have a higher risk of severe infection and associated mortality. Additional studies are needed to further evaluate this relationship.

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