Obesity is associated with increased severity of disease in COVID-19 pneumonia: a systematic review and meta-analysis

Obesity has been widely reported to be associated with the disease progression of coronavirus disease 2019 (COVID-19) Body mass index (BMI) was higher in severe/critical patients, obesity did not increase the risk of hospital mortality.

Rehabilitation and COVID-19: a rapid living systematic review 2020 by Cochrane Rehabilitation Field. Update as of September 30th, 2020

Most studies described patients in the acute (51.4%) or subacute (35.0%) phase. No studies described the chronic consequences of COVID-19. Research focuses more on describing clinical presentations and the natural history of the pathology.

Clinical characteristics and outcomes of pregnant women with COVID-19 and the risk of vertical transmission: a systematic review

34.62% of the pregnant patients had obstetric complications, and 59.05% of patients displayed fever. 24.74% of newborns were premature, and 5 newborns throat swab tests of SARS-CoV-2 were positive, all of which were delivered by cesarean section.

Convalescent plasma may be a possible treatment for COVID-19: A systematic review

Convalescent plasma(CP) immunotherapy was an effective method for fighting against SARS-CoV and MERS- CoV. There is controversy over the efficacy of CP therapy for the coronavirus disease 2019 (COVID) pandemic

Persistence of symptoms and quality of life at 35 days after hospitalization for COVID-19 infection

The study seeks to identify persistent symptoms in patients 35 days post-hospitalization. 183 patients (median age 57 years; 61.5% male, 54.1% white) reported persistent symptoms at 35 days.

Bariatric Surgery Reduces Cancer Risk in Adults with Nonalcoholic Fatty Liver Disease and Severe Obesity

Nonalcoholic fatty liver disease (NAFLD) is associated with obesity and an increased risk of cancer. We investigated the effect of bariatric surgery on cancer risk in patients with NAFLD and severe obesity

Sequential administration of XPO1 and ATR inhibitors enhances therapeutic response in TP53-mutated colorectal cancer

The authors conducted a patient-centered functional genomics platform that includes approximately 200 genes. Administration of KPT-8602, an XPO1 inhibitor, followed by AZD-6738, an ATR inhibitor, resulted in dramatic antitumor effects and prolonged survival.

Neutrophils Alter DNA Repair Landscape to Impact Survival and Shape Distinct Therapeutic Phenotypes of Colorectal Cancer

Neutrophils can increase DNA double-strand breaks (DSB) burden and promote genomic instability in colorectal cancer. They can also promote HR deficiency by miR-155-dependent downregulation of RAD51

Departments

Recent Posts