Efficacy and Safety of a New Botulinum Toxin (HU-014) Versus Existing Onabotulinumtoxin A in Subjects With Moderate to Severe Glabellar Lines

The safety of a new botulinum toxin (HU-014) was confirmed through animal experiments. HU-014 was non-inferior to existing on botulinum toxin A in the treatment of glabellar lines at a 1:1 dose ratio.

Five-Year Outcomes of Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy: A Randomized Clinical Trial

0.5-mg intravitreous ranibizumab vs pan-retinal photocoagulation (PRP) over 5 years for PDR. Secondary outcomes included peripheral visual field loss, development of vision-impairing diabetic macular edema, and ocular and systemic safety.

Maternal Depressive Symptoms Predict Girls’ but Not Boys’ Emotion Regulation: A Prospective Moment-to-Moment Observation Study

The study looked at 108 mother-child dyads from three to four years old. Higher levels of maternal depressive symptoms predicted faster transitions into sadness only for girls but not for boys. Girls of mothers with elevated depressive symptoms showed impairment in antecedent-focused emotion regulation of sadness.

Neuropathology of patients with COVID-19 in Germany: a post-mortem case series

It is unclear whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) gains access to the CNS. We investigated the brain tissue of patients who died from COVID-19 for glial responses, inflammatory changes, and the presence of SARS- CoV- 2 in the brain. There was no evidence of CNS damage directly caused by the virus. The generalisability of these findings needs to be validated in future studies.

New-onset myocardial injury in pregnant patients with coronavirus disease 2019: a case series of 15 patients

Severe acute respiratory syndrome coronavirus 2 causes cardiac injury in nonpregnant women. The study retrospectively reviewed the paper records of 15 pregnant women with coronavirus disease in 2019, who developed a myocardial injury in a single tertiary care hospital in the Dominican Republic. The study showed coronavirus disease 2019 induced myocardial injury and left ventricular dysfunction in pregnant women.

Clinical characteristics and long-term outcomes of endovascular treatment of renal artery fibromuscular dysplasia with branch lesions

Renal artery fibromuscular dysplasia (FMD) can cause arterial stenosis, dissection, and aneurysm of renal arteries. The incidence of branch FMD was higher in children than in adults. Endovascular treatment with balloon angioplasty can be used to treat FMD.

Korean rheumatology workforce from 1992 to 2015: current status and future demand

Rheumatology in Korea has rapidly advanced in the 24 years since the subspecialty board certification program was established. In 2015, there were 311 practicing rheumatologists on the list of KCR members.

National Radiation Oncology Medical Student Clerkship Trends From 2013 to 2018

This study assesses national trends in fourth-year medical student radiation oncology clerkships over the past 6 academic years. Over half of clerkship experiences continue to lack a structured didactic curriculum.

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