Prevalence and characteristics of fever in adult and paediatric patients with coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis of 17515 patients
Coronavirus disease 2019 started to spread globally in December 2019 from Wuhan, China. Fever has been observed as one of the most common clinical manifestations. 167 studies with 17142 adults and 373 pediatrics were included. The pooled prevalence of fever in adult and pediatric COVID-19 patients was 79.43% and 45.86% respectively. The prevalence of fever in adult COVID-19 patients was high & pediatric COVID-19 patients did not exhibit fever as an initial clinical feature.
Detection of SARS-CoV-2 in conjunctival secretions from patients without ocular symptoms
4/49, 8.2% were positive for SARS-CoV-2 RNA. The median duration of illness when the first conjunctival swab was obtained was 10 days (range 2-27 days) The swabs were taken from four different patients in New York City. The total number of swabs was 4/49.
A pandemic center's experience of managing pregnant women with COVID-19 infection in Turkey: A prospective cohort study
SARS-CoV-2 was suspected in 100 pregnant women. Of them, 29 had the diagnosis confirmed by RT-PCR. Eight of the remaining 71 cases had clinical findings highly suspicious for COVID-19. Cough and myalgia were the leading symptoms.
SARS-CoV-2 infection in London, England: changes to community point prevalence around lockdown time, March-May 2020
UK implemented a lockdown in March 2020, when the testing policy at the time was focusing on hospitalized cases. We assessed COVID-19 point prevalence in London between early April and early May 2020. Point prevalence decreased from 2.2% (95% CI 1.4 to 3.5) in early April to 0.2%.
Early Risk Factors for the Duration of Severe Acute Respiratory Syndrome Coronavirus 2 Viral Positivity in Patients With Coronavirus Disease 2019
Pneumonia coronavirus disease 2019 (COVID-19) has become a pandemic. Early risk factors for the duration of SARS-CoV-2 viral positivity were evaluated. Younger age, disease not being severe, higher lymphocyte counts and CD8+ T-cell counts were found to be risk factors.
Saliva samples for detection of SARS-CoV-2 in mildly symptomatic and asymptomatic patients
The ongoing coronavirus disease 2019 (Covid-19) pandemic has been rapidly spreading throughout the world with confirmed case numbers already exceeding 75 million.
Atypical presentation of COVID-19 in hospitalised older adults
Older patients with atypical presentation of COVID-19 in the community are equally susceptible to poor outcomes. Early detection may improve outcomes and limit community transmission. Primary care practitioners should be vigilant and consider prompt onward referral, authors say.
Early hydroxychloroquine but not chloroquine use reduces ICU admission in COVID-19 patients
Recent studies report no effect of (H)CQ on 28-day mortality. HCQ was associated with a significantly decreased risk of transfer to the ICU. This effect was not found in the CQ group, however.