Efficacy of Home Telemonitoring versus Conventional Follow-up: A Randomized Controlled Trial among Teenagers with Inflammatory Bowel Disease

Conventional follow-up of teenagers with IBD is done during scheduled outpatient visits regardless of how well the patient feels. We designed a telemonitoring strategy for early recognition of flares and compared its efficacy with conventional follow-ups.

Randomized phase III study of bevacizumab plus FOLFIRI and bevacizumab plus mFOLFOX6 as first-line treatment for patients with metastatic colorectal cancer (WJOG4407G)

The primary endpoint was non-inferiority of F OLFIRI + Bev to mF OLFOX6 + BeV in progression-free survival (PFS) The common grade 3 or higher adverse events were leukopenia, neutropenia, diarrhea, febrile neutropenia, peripheral neuropathy, and venous thromboembolism.

[Treatment of postprandial discomfort syndrome in the elderly: a multi-centered prospective randomized controlled clinical study]

A total of 323 patients from 16 tertiary hospitals in China were enrolled in this study. The efficacy rate in all patients after the first week of treatment was over 15.0%. After treatment, the NDSI scores in the three groups all decreased significantly.

Clinical importance of cold polypectomy during the insertion phase in the left side of the colon and rectum: a multicenter randomized controlled trial (PRESECT study)

Colorectal polyps are often detected during the insertion phase of colonoscopy but are commonly removed during the withdrawal phase. This prospective, multicenter, randomized trial targeted patients with at least 1 left-sided polyp detected unintentionally on endoscope insertion from April 2018 to March 2019.

Effectiveness and safety of vedolizumab for maintenance treatment in inflammatory bowel disease-The Israeli real world experience

Vedolizumab (VDZ) has been used for induction of remission in inflammatory bowel diseases (IBD) At week 52, the response was observed in 62/133 (46.7%) CD patients, including 28 (21%) in clinical remission.

Multifocal Cryoballoon Ablation for Eradication of Barrett's Esophagus-Related Neoplasia: A Prospective Multicenter Clinical Trial

Limited data on cryoballoon ablation (CBA) suggest its potential clinical utility. We evaluated the safety and efficacy of CBA in a multicenter study of patients with neoplastic BE.

The Effect of Dietary Intervention on Irritable Bowel Syndrome: A Systematic Review

Elimination diets have been used for many years to treat irritable bowel syndrome (IBS) These approaches had fallen out of favor until a recent resurgence.

Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial

Allogeneic, expanded, adipose-derived stem cells (Cx601) are a promising new therapeutic approach. We aimed to assess the safety and efficacy of Cx601 for treatment-refractory complex perianal fistulas in patients with Crohn's disease.

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