Effect of hydroxychloroquine with or without azithromycin on the mortality of coronavirus disease 2019 (COVID-19) patients: a systematic review and meta-analysis

Hydroxychloroquine or chloroquine with or without azithromycin have been widely promoted to treat coronavirus disease 2019 (COVID-19) The aim of this systematic review and meta-analysis was to assess whether the drugs decreased mortality compared with the standard of care

Therapeutic strategies for severe COVID-19: a position paper from the Italian Society of Infectious and Tropical Diseases (SIMIT)

Standard treatment for coronavirus disease 2019 (COVID-19) is not well defined because the evidence, either from randomized or observational studies, with conflicting results.

Convalescent plasma may be a possible treatment for COVID-19: A systematic review

Convalescent plasma(CP) immunotherapy was an effective method for fighting against similar viral infections such as SARS-CoV, and MERS- coV. There is controversy over the efficacy of CP therapy for the coronavirus disease 2019 (COVID-19) pandemic.

Homozygosity for rs17775810 Minor Allele Associated With Reduced Mortality of COVID-19 in the UK Biobank Cohort

Fluvoxamine strongly binds to the sigma-1 receptor (S1R) that regulates inflammation by inhibiting the production of cytokines, believed to be responsible for severe COVID-19.

Resource Utilization and Outcomes in Isolated Low-Grade Renal Trauma at a Level 1 Trauma Center

The study examined admission and transfer patterns of isolated low-grade renal trauma given the lack of evidence-based guidelines. All patients were discharged alive and the majority (94%) was discharged home

A Meta-Analysis and Systematic Review of the Incidences of Complications Following Facial Thread-Lifting

The swelling was the most commonly reported complication with a pooled incidence of 35%. Absorbable threads were associated with a significantly lower risk of paresthesia (3.1% vs. 11.7%) and thread extrusion (1.6%) than non-absorbable Threads.

Remote ischaemic preconditioning ameliorates anthracycline-induced cardiotoxicity and preserves mitochondrial integrity

Anthracycline-induced cardiotoxicity (AIC) is a serious adverse effect among cancer patients. The central mechanism of AIC is irreversible mitochondrial damage. Animals receiving RIPC before doxorubicin (RIPC-Doxo) had a significantly higher LVEF at Week 16 than those treated with no pretreatment (Untreated-Dxo) This was mainly due to conserved regional contractile function.

Effect of Tranexamic Acid Administration on Postoperative Ecchymosis and Edema in Excision of Lipomas

Tranexamic acid reduces bleeding during soft tissue surgeries and reduces postoperative ecchymosis and edema experienced by surgical patients.No statistical difference was seen in mean edema scores between groups.

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