Performance of the quick COVID-19 severity index and the Brescia-COVID respiratory severity scale in hospitalized patients with COVID-19 in a community hospital setting

The study was a retrospective cohort study of 313 consecutive hospitalized adult patients with coronavirus disease 2019 (COVID-19) pneumonia. The overall in-hospital fatality rate was 32.3%, and the ICU admission rate was 31.3%.

Evaluation of clinical utility of novel coronavirus antigen detection reagent, Espline® SARS-CoV-2

To prevent the novel coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2, it is necessary to perform early identification and isolation of people shedding the infectious virus in biological materials with high viral loads.

A single center cohort of 40 severe COVID-19 patients who were treated with convalescent plasma

Convalescent plasma (CP) was previously used successfully to treat SARS-CoV-1 and MERS infections. Nine out of 10 patients who have received CP outside ICU have totally recovered from COVID-19 at a median of 9 days.

Improving Detection Efficiency of SARS-CoV-2 Nucleic Acid Testing

SARS-CoV-2 nucleic acid testing (NAT) has been routinely used for diagnosis during this pandemic. There have been concerns about its high false-negative rate. We dissected its detection efficiency with a large COVID-19 cohort study.

Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2

SARS-CoV-2 has caused a worldwide pandemic of coronavirus disease 2019 or COVID-19. Coronaviruses generate subgenomic RNAs through a process involving homology between transcriptional regulatory sequences (TRS) Read-mapping was used to determine the 5' and 3' coordinates of all junctions in viral RNAs identified in these samples.

Autoimmune and Rheumatic Manifestations Associated With COVID-19 in Adults: An Updated Systematic Review

Numerous cases of the coronavirus disease 2019 (COVID-19) with autoimmune and rheumatic manifestations have been reported. Most of the existing evidence was based on case reports or case series without a long-term follow-up.

Induction with NCB-02 (curcumin) enema for mild-to-moderate distal ulcerative colitis - a randomized, placebo-controlled, pilot study

Curcumin, an active ingredient of turmeric with anti-inflammatory properties, has been demonstrated to be useful in experimental models of ulcerative colitis (UC). It's efficacy in humans needs to be investigated.

Efficacy of intramuscular diclofenac and fluid replacement in prevention of post-ERCP pancreatitis

The study was conducted on 80 patients who underwent ERCP. The overall incidence of pancreatitis was 7.5% in the diclofenac group and 17.5 percent in the placebo group.

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