COVID-19 associated with severe autoimmune hemolytic anemia
Autoimmune hemolytic anemia (AIHA) has many known disease associations, including autoimmune, lymphoproliferative, and certain infectious diseases. Studies have found that severe cases of coronavirus disease 2019 (COVID-19) may be associated with coagulopathies; however, the potential association with AIHA is not clear
A systematic review and meta-analysis of published research data on COVID-19 infection fatality rates
An important unknown during the coronavirus disease- 2019 (COVID-19) pandemic has been the infection fatality rate (IFR) IFR is increasingly being called for by policy makers and the lay public as an estimate of the overall mortality from COVID- 19.
Robotic Peritoneal Flap Revision Vaginoplasty in Transgender Women: a Novel Technique for Treating Neovaginal Stenosis
24 patients underwent robotic peritoneal flap revision vaginoplasty from 2017-2020. At a mean follow-up of 410 days, vaginal depth and width were 13.6 cm and 3.6cm, respectively.
Long-term National Trends of Arthroscopic Meniscal Repair and Debridement
The study looked at arthroscopic meniscal debridement and repair practice trends among ABOS Part II examinees from 2001 to 2017. Debridement volume decreased for all age groups during the study period, while repair increased.
Effect of icosapent ethyl on progression of coronary atherosclerosis in patients with elevated triglycerides on statin therapy: a prospective, placebo-controlled randomized trial (EVAPORATE): interim results
ICosapent ethyl (IPE) added to statin therapy reduced initial CV events by 25% and total CV Events by 30% in the REDUCE-IT study. The study is the first to evaluate the effects of IPE on atherosclerotic plaque characteristics in a high-risk CV population with persistently high triglyceride levels.
Attitudes on Prophylactic Antibiotic Use in Dermatologic Surgery: A Survey Study of American College of Mohs Surgery Members
75.25% (76/101) of surgeons reported routinely prescribing prophylactic antibiotics to reduce SSI risk. 90.63% indicated an interest in clinical trial data evaluating the efficacy of oral antibiotics.
The role of polymorphisms rs2070744 and rs1799983 eNOS gene in patients with POAG: a systematic review and meta-analysis
Glaucoma is a progressive disease of the optic nerve that has several underlying causes. The eNOS gene polymorphisms may increase the risk of POAG among individuals. Further studies are needed to confirm these findings
Cell-type-specific synaptic imbalance and disrupted homeostatic plasticity in cortical circuits of ASD-associated Chd8 haploinsufficient mice
Heterozygous mutation of chromodomain helicase DNA binding protein 8 (CHD8) is strongly associated with autism spectrum disorder (ASD) It results in dysregulated expression of neurodevelopmental and synaptic genes during brain development. We studied how these changes affect ASD-associated cortical circuits in a mouse model.